(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylicAcidMethylEster | CAS No. 1987887-92-2

(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylicAcidMethylEster

Basic Information

CAS Number

1987887-92-2

Molecular Formula

C24H21N3O3

Molecular Weight

399.44 g/mol

AD

Basic Physical Properties

N1C2=C(C=CC(C(OC)=O)=C2)/C(=C(/NC2=CC=C(NC)C=C2)\C2=CC=CC=C2)/C1=O

InChI

1S/C24H21N3O3/c1-25-17-9-11-18(12-10-17)26-22(15-6-4-3-5-7-15)21-19-13-8-16(24(29)30-2)14-20(19)27-23(21)28/h3-14,25-26H,1-2H3,(H,27,28)/b22-21-

InChIKey

KASRBMLHGYYOMZ-DQRAZIAOSA-N

LogP

4.447400000000003

Topological Polar Surface Area

79.46000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Synonyms & References

English

  • (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • Intedanib Impurity D
  • Nintedanib Impurity 34
  • Nintedanib-011
  • Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...
  • 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-
  • Nintedanib Impurity q
  • methyl (Z)-3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

FAQ

What is (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (CAS: 1987887-92-2)?

(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester, also known as DMIA, is a chemical compound with the CAS number 1987887-92-2. It is a derivative of indole with a specific molecular structure that includes a methyl ester group and amino substituents, making it suitable for various applications in pharmaceuticals and research.

What are the main uses of (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (CAS: 1987887-92-2)?

(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (DMIA) is primarily used in pharmaceutical research for its potential as a medicinal compound. It is also utilized in the development of new drugs and as a precursor in chemical synthesis.

Is (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (CAS: 1987887-92-2) safe?

(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (DMIA) is generally considered safe under controlled conditions. However, it should be handled with caution due to its potential toxicity. Proper protective measures, including gloves and lab coats, should be worn during handling. Storage in a cool, dry place away from direct sunlight is recommended.

How should (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (CAS: 1987887-92-2) be stored?

(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester (DMIA) should be stored in tightly sealed containers to protect it from moisture and light. It should be kept in a cool, dry place with a temperature range of 15-25°C and away from direct sunlight. Proper labeling and storage conditions are essential to ensure its stability and safety.

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