Bazedoxifene Acetate

Basic Information

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CAS Number

198481-33-3

Molecular Formula

C32H38N2O5

Molecular Weight

530.67 g/mol

EINECS

638-804-4

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

white to beige

Melting Point

174-178°

Boiling Point

No data available

Flash Point

No data available

Solubility

DMSO: soluble15mg/mL, clear

Vapor Pressure

No data available

SMILES

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Cc1c2cc(ccc2n(c1c3ccc(cc3)O)Cc4ccc(cc4)OCCN5CCCCCC5)O.CC(=O)O

InChI

InChI=1S/C30H34N2O3.C2H4O2/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31;1-2(3)4/h6-15,20,33-34H,2-5,16-19,21H2,1H3;1H3,(H,3,4)

InChIKey

OMZAMQFQZMUNTP-UHFFFAOYSA-N

LogP

6.421920000000007

Topological Polar Surface Area

95.16000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Synonyms & References

English

BAZEDOXIFENE ACETATE
1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol monoacetate (salt)
1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-, monoacetate (salt)
Bazedoxifene acetate [usan]
Unii-J70472ud3d
Viviant
Way-140424
1-((4-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol monoacetate
acetic acid,1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol
TSE 424
WAY-TES 424
1-[4-(2-Azepan-1-yl-ethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate
TSE-424
WAY-TSE-424
3-Oxo Ziprasidone
Bazedoxifene acetat
TSE-424 acetate
WAY-140424
Bazedoxifene acetate
1-(4-(2-(Azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
acetate (1:1)

MDL Number

MFCD09260074

EC Number

638-804-4

FAQ

What regulatory guidelines apply to Bazedoxifene Acetate (CAS: 198481-33-3)?

Bazedoxifene Acetate (CAS: 198481-33-3) is subject to various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a pharmaceutical substance and must comply with the relevant safety data sheets (SDS) and material safety data sheets (MSDS) under GHS. REACH regulations require detailed documentation of its production, import, and supply chain. FDA and EPA regulations ensure its safe handling and disposal to protect public health and the environment.

Are there alternatives to Bazedoxifene Acetate (CAS: 198481-33-3) in synthesis?

Alternatives to Bazedoxifene Acetate (CAS: 198481-33-3) in synthesis include other selective estrogen receptor modulators (SERMs) like raloxifene acetate and tamoxifene acetate. These compounds offer similar pharmacological profiles and can be used as substitutes depending on the specific requirements of the synthesis. Other common alternative reagents include various acetic anhydrides and acetic acids, which can serve as acetate forming agents for similar compounds.

What is the market or research trend for Bazedoxifene Acetate (CAS: 198481-33-3)?

The market for Bazedoxifene Acetate (CAS: 198481-33-3) reflects ongoing research and development in estrogen receptor modulators for treatments such as osteoporosis and menopausal symptoms. Recent trends indicate increased interest in understanding its mechanisms and optimizing its therapeutic window. Research trends also focus on comparative studies with existing SERMs and exploring its potential in combination therapies. Market demand is driven by growing elderly populations and increasing awareness of menopausal health issues.

How should waste containing Bazedoxifene Acetate (CAS: 198481-33-3) be handled?

Waste containing Bazedoxifene Acetate (CAS: 198481-33-3) should be collected in appropriate containers and labeled with specific hazard warnings. Proper incineration or professional waste disposal services should be utilized to ensure safe disposal. Environmental protection measures include minimizing spillage and ensuring containers are sealed to prevent leaks. It is crucial to follow local and national regulations for hazardous waste disposal to protect public health and the environment.