2-Fluoro-3-methylaniline

Basic Information

View in Editor

CAS Number

1978-33-2

Molecular Formula

C7H8FN

Molecular Weight

125.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

87°C/12mmHg

Flash Point

62.9℃

Refractive Index

1.5340-1.5380

SMILES

View in Editor

CC1=C(C(=CC=C1)N)F

InChI

InChI=1S/C7H8FN/c1-5-3-2-4-6(9)7(5)8/h2-4H,9H2,1H3

InChIKey

WFZUBZAEFXETBF-UHFFFAOYSA-N

LogP

1.71632

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

94.9

Safety Information

View Safety Information

Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

BENZENAMINE, 2-FLUORO-3-METHYL-
PS-9199
1978-33-2
MFCD06410915
DTXSID00627933
AB25121
EN300-126352
SCHEMBL406513
FT-0601392
J-511540
2-Fluoro-m-toluidine
A4332
AKOS005145718
F0554
2-fluoro-3-methylbenzenamine;2-Fluoro-3-methylaniline
SY018333
WFZUBZAEFXETBF-UHFFFAOYSA-N
3-amino-2-fluorotoluene
2-fluoro-3-methylbenzenamine
AC-3378
AM20050318
2-Fluoro-3-methylaniline
CS-W003289
2-Fluoro-3-methyl-phenylamine
3-Amino-2-fluorotoluene
2-Fluor-3-methyl-anilin
2-Fluor-m-toluidin
2-fluoro-3-aminotoluene
2-fluoro-3-methyl-aniline
2-fluoro-3-methylphenylamine
Benzenamine, 2-fluoro-3-methyl-

MDL Number

MFCD06410915

Customs Code

2921430090

FAQ

What are the physical and chemical properties of 2-Fluoro-3-methylaniline (CAS: 1978-33-2)?

2-Fluoro-3-methylaniline (CAS: 1978-33-2) is a crystalline solid with a molecular weight of approximately 140.04 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It has a melting point of 55-57°C and is reactive towards nucleophiles and electrophiles. It can undergo electrophilic aromatic substitution reactions and nucleophilic substitution at the methyl group.

How is 2-Fluoro-3-methylaniline (CAS: 1978-33-2) typically synthesized?

2-Fluoro-3-methylaniline (CAS: 1978-33-2) is typically synthesized by the reaction of 3-methylaniline with hydrofluoric acid or by the alkylation of 2-fluoroaniline with methyl iodide in the presence of a catalyst such as sodium hydride. The reaction yields a mixture that requires purification techniques such as recrystallization and chromatography to obtain the pure compound.

What industries use 2-Fluoro-3-methylaniline (CAS: 1978-33-2)?

2-Fluoro-3-methylaniline (CAS: 1978-33-2) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of functionalized polymers, and in the chemical sensors industry for the development of sensor materials. It also finds applications in the semiconductor industry as an intermediate in the production of certain organic semiconductors.

What precautions should be taken when handling 2-Fluoro-3-methylaniline (CAS: 1978-33-2)?

When handling 2-Fluoro-3-methylaniline (CAS: 1978-33-2), appropriate personal protective equipment (PPE) should be used, including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure to vapors. In case of a spill, it should be cleaned up using appropriate absorbents and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.