8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Basic Information

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CAS Number

19685-84-8

Molecular Formula

C11H11ClN2

Molecular Weight

206.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CNCC2=C1NC3=C2C=C(C=C3)Cl

InChI

InChI=1S/C11H11ClN2/c12-7-1-2-10-8(5-7)9-6-13-4-3-11(9)14-10/h1-2,5,13-14H,3-4,6H2

InChIKey

LCKUBQBEDRQTRC-UHFFFAOYSA-N

LogP

2.4670000000000005

Topological Polar Surface Area

27.82 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

221

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

MLS001164788
EN300-44289
AB12745
Oprea1_258483
HMS2860C10
8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]-indole
SCHEMBL2313213
MFCD02930875
LCKUBQBEDRQTRC-UHFFFAOYSA-N
8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
ST077718
8-chloro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole
FT-0747081
Z382721670
VS-09429
CS-0270663
AKOS000302752
D78553
CHEMBL1709723
19685-84-8
SMR000539953
1H-Pyrido[4,3-b]indole,8-chloro-2,3,4,5-tetrahydro-
8-chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(SALTDATA: 0.04NaCl)
8-Chlor-2,3,4,5-tetrahydro-1H-pyrido<4,3-b>indol
8-chloro-2,3,4,5-tetrahydro-1H-pyrido<4,3-b>indole
AKOS JY2083657
TIMTEC-BB SBB004415
CHEMBRDG-BB 4002721

MDL Number

MFCD02930875

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS: 19685-84-8)?

8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a crystalline solid with a molecular weight of approximately 257.01 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and methanol. The compound is known for its chemical stability and low reactivity under normal conditions, making it suitable for various applications.

How is 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS: 19685-84-8) typically synthesized?

8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is usually synthesized through a multi-step process involving the coupling of 8-chloroquinoline with an aldehyde in the presence of a base like sodium hydride. The reaction proceeds via an organometallic intermediate, followed by a ring-closure step to form the indole ring. The overall yield is typically around 60-70%.

What industries use 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS: 19685-84-8)?

8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole finds applications in the pharmaceutical industry, particularly in the development of certain medicinal compounds. It is also used in the synthesis of fluorescent dyes for sensors and semiconductors due to its optical properties.

What precautions should be taken when handling 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS: 19685-84-8)?

When handling 8-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole, it is important to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and eye protection. The compound should be stored in a fume hood to minimize inhalation risks. In case of a spill, use appropriate cleanup procedures and consult the Safety Data Sheet (SDS) for detailed instructions.