4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol

Basic Information

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CAS Number

196603-96-0

Molecular Formula

C15H11BrFN3O2

Molecular Weight

364.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

470.9°C at 760 mmHg

SMILES

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COc1cc2c(cc1O)ncnc2Nc3ccc(cc3F)Br

InChI

InChI=1S/C15H11BrFN3O2/c1-22-14-5-9-12(6-13(14)21)18-7-19-15(9)20-11-3-2-8(16)4-10(11)17/h2-7,21H,1H3,(H,18,19,20)

InChIKey

XIHOMGRMQWNHHB-UHFFFAOYSA-N

LogP

3.989200000000001

Topological Polar Surface Area

67.27 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

379

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol
4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxy-7-Quinazolinol
4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline
4-(4-bromo-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazoline
7-QUINAZOLINOL, 4-[(4-BROMO-2-FLUOROPHENYL)AMINO]-6-METHOXY-
QC-1062
4-(4-bromo-2-fluorophenylamino)-6-methoxyquinazolin-7-ol
6-Methoxy-7-hydroxy-4-(2''-fluoro-4''-broMoaniline)quinazoline
AK120803
4-(4-bromo-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one
4-[(4-bromo-2-fluorophenyl)amino]-6-methoxyquinazolin-7-ol
XIHOMGRMQWNHHB-UHFFFAOYSA-N
BCP16090
A

MDL Number

MFCD09955370

Customs Code

2933990090

FAQ

What is 4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol (CAS: 196603-96-0)?

4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol is an organic compound with the CAS number 196603-96-0. It is a quinazolinone derivative with a bromo and fluoro substituent on the anilino group and a methoxy group attached to the quinazolinone ring. This compound is characterized by its aromatic structure and potential biological activity.

What are the main uses of 4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol (CAS: 196603-96-0)?

4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol is primarily used in the pharmaceutical industry as a potential lead compound for drug development. It may also be used in research for studying biological activities and interactions with specific targets.

Is 4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol (CAS: 196603-96-0) safe?

4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol is generally considered safe for laboratory use with appropriate handling precautions. However, it is important to follow safety guidelines, including wearing appropriate personal protective equipment (PPE) and ensuring proper ventilation. Avoid skin and eye contact, and store in a well-ventilated area away from heat sources and direct sunlight.

How should 4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol (CAS: 196603-96-0) be stored?

4-(4-bromo-2-fluoro-anilino)-6-methoxy-quinazolin-7-ol should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Optimal storage conditions include a temperature range of 15-25°C and a relative humidity below 60%. Proper labeling and storage in a secure and accessible location are also recommended for safety reasons.