4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl | CAS No. 1957235-66-3

4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Basic Information

CAS Number

1957235-66-3

Molecular Formula

C15H16N4O4

Molecular Weight

316.31 g/mol

AD

Basic Physical Properties

Cl[H].O=C1C2C(=C([H])C([H])=C([H])C=2C(N1C1([H])C(N([H])C(C([H])([H])C1([H])[H])=O)=O)=O)N([H])C([H])([H])C([H])([H])N([H])[H]

InChI

1S/C15H16N4O4.ClH/c16-6-7-17-9-3-1-2-8-12(9)15(23)19(14(8)22)10-4-5-11(20)18-13(10)21;/h1-3,10,17H,4-7,16H2,(H,18,20,21);1H

InChIKey

DSJCOXQYDMWPEY-UHFFFAOYSA-N

LogP

-0.11980000000000068

Topological Polar Surface Area

121.60000000000001 Ų

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

550

Synonyms & References

English

  • Pomalidomide-C2-NH2 (hydrochloride)
  • 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
  • 4-((2-Aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
  • Pomalidomide-C2-NH2

FAQ

What are the physical and chemical properties of 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl (CAS: 1957235-66-3)?

This compound is a white crystalline solid with a molecular weight of approximately 458.5 g/mol. It has a high solubility in water and poor solubility in organic solvents. Chemically, it is stable under normal conditions but may react with strong acids and bases. It is characterized by its amine and amide functionalities, which make it reactive in various synthetic conditions.

How is 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl (CAS: 1957235-66-3) typically synthesized?

This compound is typically synthesized by the condensation of 2-aminoethylamine with 2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione under basic conditions. The reaction involves the use of a suitable base such as sodium hydroxide, and the yield is usually high. The product is then converted to the hydrochloride salt using hydrogen chloride gas.

What industries use 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl (CAS: 1957235-66-3)?

This compound is primarily used in the pharmaceutical industry for its potential as a drug candidate due to its unique chemical structure. It also has applications in polymer chemistry, where it can be used as a curing agent, and in the development of sensors and semiconductors for their specific functional properties.

What precautions should be taken when handling 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl (CAS: 1957235-66-3)?

Proper personal protective equipment (PPE) should always be worn when handling this compound, including gloves, safety goggles, and a lab coat. Ensure that all work is conducted in a well-ventilated area, such as a fume hood, to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Access the safety data sheet (SDS) for specific handling instructions and emergency procedures.

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