Compound Q&A

How is 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl (CAS: 1957235-66-3) typically synthesized?

Answer

4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
This compound is typically synthesized by the condensation of 2-aminoethylamine with 2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione under basic conditions. The reaction involves the use of a suitable base such as sodium hydroxide, and the yield is usually high. The product is then converted to the hydrochloride salt using hydrogen chloride gas.

About

English Name 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Molecular Formula C15H16N4O4
Molecular Weight 316.31 g/mol
SMILES Cl[H].O=C1C2C(=C([H])C([H])=C([H])C=2C(N1C1([H])C(N([H])C(C([H])([H])C1([H])[H])=O)=O)=O)N([H])C([H])([H])C([H])([H])N([H])[H]
InChIKey DSJCOXQYDMWPEY-UHFFFAOYSA-N
Last Updated: 2026-03-01 17:11

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