Amiodarone EP Impurity D (Amiodarone USP Related Compound D)

Basic Information

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CAS Number

1951-26-4

Molecular Formula

C19H16I2O3

Molecular Weight

546.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

143.0 to 147.0 deg-C

Boiling Point

536.8 °C at 760 mmHg

Flash Point

278.4 °C

Refractive Index

1.696

SMILES

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CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)O)I

InChI

InChI=1S/C19H16I2O3/c1-2-3-7-16-17(12-6-4-5-8-15(12)24-16)18(22)11-9-13(20)19(23)14(21)10-11/h4-6,8-10,23H,2-3,7H2,1H3

InChIKey

PNFMEGSMKIHDFZ-UHFFFAOYSA-N

LogP

5.921200000000004

Topological Polar Surface Area

50.44 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

432

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Z2301679756
1951-26-4
NSC 85437
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran
AC-13412
4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenol
L 3373
A813783
(2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)ketone
CHEBI:79661
2-butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofurane
2-butyl-3-[3,5-diiodo-4-hydroxybenzoyl]benzofuran
AMIODARONE HYDROCHLORIDE IMPURITY D [EP IMPURITY]
2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzo-furan
(2-Butyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)methanone
BDBM18962
D8YC83C05N
AS-12154
(2-Butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone
NSC85437
MFCD02675787
NSC-85437
2-n-Butyl-3-(3,5-diiodo-4-hydroxy benzoyl) benzofuran
W-107694
Methanone, (2-butyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-
(2-butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
Amiodarone impurity D
DTXSID20173164
CHEMBL3526986
Q27148784
L3373

MDL Number

MFCD02675787

Customs Code

2932999099

FAQ

What is Amiodarone EP Impurity D (CAS: 1951-26-4)?

Amiodarone EP Impurity D, also known as Amiodarone USP Related Compound D (CAS: 1951-26-4), is a congeners of the antiarrhythmic drug amiodarone. It is a minor impurity found in amiodarone formulations and is characterized by its chemical structure similar to that of amiodarone.

What are the main uses of Amiodarone EP Impurity D (CAS: 1951-26-4)?

Amiodarone EP Impurity D is primarily used in the pharmaceutical industry as a reference material for the quality control and testing of amiodarone formulations. It helps ensure that amiodarone products meet the required standards and specifications.

Is Amiodarone EP Impurity D (CAS: 1951-26-4) safe?

Amiodarone EP Impurity D is generally considered safe under controlled laboratory conditions. However, like any chemical substance, it should be handled with appropriate precautions, such as wearing protective gloves and goggles. Exposure to the skin or inhalation should be avoided.

How should Amiodarone EP Impurity D (CAS: 1951-26-4) be stored?

Amiodarone EP Impurity D should be stored in a tightly closed container in a cool, dry place, away from direct sunlight and heat sources. The storage temperature should not exceed 25°C, and the relative humidity should be kept below 60% to prevent degradation and ensure stability.