6-Methyleneandrost-4-ene-3,17-dione

Basic Information

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CAS Number

19457-55-7

Molecular Formula

C20H26O2

Molecular Weight

298.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

450.8°C at 760 mmHg

Density

1.11

Flash Point

168 °C

Refractive Index

1.555

SMILES

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CC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)CCC34C

InChI

InChI=1S/C20H26O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h11,14-16H,1,4-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChIKey

KQRGETZTRARSMA-DAELLWKTSA-N

LogP

4.253500000000003

Topological Polar Surface Area

34.14 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

613

Safety Information

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GHS Hazard Pictograms

H361

Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

M3121
KQRGETZTRARSMA-DAELLWKTSA-N
DTXSID90513775
Androst-4-ene-3,17-dione, 6-methylene-
19457-55-7
6-Methylen-androst-4-ene-3,17-dione
93RDL2KVK2
6-Methylideneandrost-4-ene-3,17-dione
D87922
AKOS015963234
6-methyleneandrost-4-ene-3,17-dione
MFCD09038727
(3AS,3BR,9AR,9BS,11AS)-9A,11A-DIMETHYL-5-METHYLIDENE-2H,3H,3AH,3BH,4H,8H,9H,9BH,10H,11H-CYCLOPENTA[A]PHENANTHRENE-1,7-DIONE
(3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-5-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7-dione
1,2-Dihydro Exemestane
C20H26O2
6-Methyleneandrost-4-en-3,17-dione
EXEMESTANE IMPURITY E [EP IMPURITY]
DS-6808
SCHEMBL349056
6-methylenandrost-4-en-3,17-dione
6-methylene-androst-4-ene-3,17-dione
6-methyleneandrosta-4-ene-3,17-dione
CS-0158056
6-methylenandrost-4-ene-3,17-dione
(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
6-methylene-4-androsten-3,17-dione
6-Methyleneandrost-4-ene-3,17-dione
Androst-4-ene-3,17-dione-6-methylene
6-methylene-4-androstene-3,17-dione
6-METHYLENEANDROST-4-ENE-3,17-DIONEENTERPRISE STANDARD

MDL Number

MFCD09038727

FAQ

What are the physical and chemical properties of 6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7)?

6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7) is a solid at room temperature with a crystalline form. It has a molecular weight of approximately 316.46 g/mol and is only slightly soluble in water. The compound is stable under normal laboratory conditions but reacts readily with strong acids and bases. It is also sensitive to light and heat, requiring storage in a cool, dark environment.

How is 6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7) typically synthesized?

6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7) is synthesized through multiple pathways, typically involving the reaction of androst-4-ene-3,17-dione with methylene chloride under the presence of a Lewis acid catalyst. The reaction is selective and yields a high purity product, making it a common method for industrial production.

What industries use 6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7)?

6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7) is primarily used in the pharmaceutical industry for the synthesis of steroidal compounds. It is also applied in the polymer industry for the development of certain types of plastics and in the semiconductor industry for electronic applications.

What precautions should be taken when handling 6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7)?

When handling 6-Methyleneandrost-4-ene-3,17-dione (CAS: 19457-55-7), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. Storage should be in a cool, dark place, and the compound should be kept away from sources of heat and light. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.