Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate | CAS No. 194282-66-1

Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate

Basic Information

CAS Number

194282-66-1

Molecular Formula

C18H16ClNO6

Molecular Weight

377.78 g/mol

AD

Basic Physical Properties

CCOC(=O)C1=C(Oc2c(=O)cc(oc2C1c3ccc(cc3)Cl)CO)N

InChI

InChI=1S/C18H16ClNO6/c1-2-24-18(23)14-13(9-3-5-10(19)6-4-9)16-15(26-17(14)20)12(22)7-11(8-21)25-16/h3-7,13,21H,2,8,20H2,1H3

InChIKey

PZMAVCPAPLFDKJ-UHFFFAOYSA-N

LogP

2.0432

Topological Polar Surface Area

111.99000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 7

Synonyms & References

English

  • ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate
  • WAY-324924
  • ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carboxylate

FAQ

What are the physical and chemical properties of Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS: 194282-66-1)?

Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate is a crystalline compound with a molecular weight of approximately 365.03 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is moderately reactive, particularly with nucleophiles, and is stable under normal conditions but should be stored in a cool, dry place away from strong acids and bases. The CAS number is 194282-66-1.

How is Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS: 194282-66-1) typically synthesized?

Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate is synthesized through a multistep process involving the condensation of amino compounds with chlorophenols, followed by the introduction of the hydroxymethyl group and the formation of the pyran ring. Commonly, this involves use of protecting groups and catalytic conditions. The yield and selectivity can be optimized using appropriate solvents and catalysts. The CAS number is 194282-66-1.

What industries use Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS: 194282-66-1)?

Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate finds applications in the pharmaceutical industry for its potential use in drug synthesis and as an intermediate. It is also explored in the development of new materials and sensors. The CAS number is 194282-66-1.

What precautions should be taken when handling Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS: 194282-66-1)?

When handling Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate, it is important to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. It should be stored in a cool, dry place away from strong acids and bases. In case of spill, it should be cleaned up with caution using appropriate absorbents. Safety data sheets (SDS) should be consulted for detailed information on handling and disposal. The CAS number is 194282-66-1.

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