(2,5-Difluorophenyl)boronic acid

Basic Information

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CAS Number

193353-34-3

Molecular Formula

C6H5BF2O2

Molecular Weight

157.91 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

105-110 °C

Boiling Point

271.3℃ at 760 mmHg

Density

1.3500

Flash Point

117.9℃

SMILES

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B(C1=C(C=CC(=C1)F)F)(O)O

InChI

InChI=1S/C6H5BF2O2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H

InChIKey

KTOJGSDLJNUAEP-UHFFFAOYSA-N

LogP

-0.35540000000000005

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

134

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AM20060168
2,5-Difluorobenzeneboronic Acid
2,5-difluorophenyl boronic acid
25-Difluorophenylboronic acid
BORONIC ACID, (2,5-DIFLUOROPHENYL)-
AKOS000285052
A16025
CS-0007591
2,5-Difluorophenylboronic acid
2,5-Difluorophenylboronicacid
KTOJGSDLJNUAEP-UHFFFAOYSA-N
DS-0468
EN300-117464
2,5-difluorobenzene boronic acid
MFCD01863171
(2,5-difluorophenyl)boronic Acid
AKOS BRN-0301
2,5-difluorophenyl-boronic acid
Z381541020
SCHEMBL4963
FT-0610350
J-507344
SY005772
(2,5-difluorophenyl)boronicAcid
193353-34-3
2,5-fluorobenzene boronic acid
2,5-difluoro phenylboronic acid
D3436
2,5-DIFLURORBENZENE BORONIC ACID
AC-5378
2,5-difluoro-phenylboronic acid

MDL Number

MFCD01863171

Customs Code

2931900090

FAQ

What are the physical and chemical properties of (2,5-Difluorophenyl)boronic acid (CAS: 193353-34-3)?

(2,5-Difluorophenyl)boronic acid is a white or off-white crystalline solid with a molecular weight of approximately 215.08 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and acetonitrile. This compound is used as a building block in organic synthesis and displays specific reactivity towards boron-containing compounds, making it suitable for various reactions.

How is (2,5-Difluorophenyl)boronic acid (CAS: 193353-34-3) typically synthesized?

(2,5-Difluorophenyl)boronic acid can be synthesized via a variety of methods. Commonly, it is produced by reacting 2,5-difluorophenol with boron tribromide followed by treatment with sodium borohydride. This synthesis provides good yield and selectivity, making it a reliable method for obtaining this compound in the laboratory and industrial settings.

What industries use (2,5-Difluorophenyl)boronic acid (CAS: 193353-34-3)?

(2,5-Difluorophenyl)boronic acid is utilized in several industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of pharmaceuticals; polymers, where it can be used as a monomer or additive; and in sensors and semiconductors, where its unique properties make it valuable for specific applications.

What precautions should be taken when handling (2,5-Difluorophenyl)boronic acid (CAS: 193353-34-3)?

When handling (2,5-Difluorophenyl)boronic acid, it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat to protect against skin and eye contact. Work should be conducted in a fume hood to minimize inhalation. Spills should be cleaned up carefully using appropriate procedures, and the material safety data sheet (MSDS) should be consulted for detailed guidelines on safe handling and disposal.