5-Bromo-2-furaldehyde

Basic Information

View in Editor

CAS Number

1899-24-7

Molecular Formula

C5H3BrO2

Molecular Weight

174.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

80.0 to 84.0 deg-C

Boiling Point

112°C/16mmHg

Flash Point

112°C/6mm

Refractive Index

1.4450 (estimate)

SMILES

View in Editor

C1=C(OC(=C1)Br)C=O

InChI

InChI=1S/C5H3BrO2/c6-5-2-1-4(3-7)8-5/h1-3H

InChIKey

WJTFHWXMITZNHS-UHFFFAOYSA-N

LogP

1.8546

Topological Polar Surface Area

30.21 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

94.4

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

Air Sensitive

Synonyms & References

English

5-Bromo-2-furaldehyde
2-Furancarboxaldehyde, 5-bromo-
STR06646
InChI=1/C5H3BrO2/c6-5-2-1-4(3-7)8-5/h1-3
A15337
FT-0620093
2-Bromofuran-5-carboxaldehyde
AM20090109
5-bromofuran-2-carbaldehyde
Furfural, 5-bromo-
CS-W007397
SCHEMBL70088
5-Bromo-2-furaldehyde, 97%
5-bromofurancarboxaldehyde
AC-25746
J-640025
5-Bromofurfural
DTXSID40344910
FD17060
5-bromo-furan-2-yl formaldehyde
5-bromofuran-2-carboxaldehyde
5-bromo-2-furfural
BCP27040
F2190-0732
2-bromofuran-5-aldehyde
J-800027
Q-101287
EN300-17810
2-Furaldehyde, 5-bromo-
AKOS000103817
5-bromo-2-formylfuran

MDL Number

MFCD00159501

Customs Code

2932190090

FAQ

What are the physical and chemical properties of 5-Bromo-2-furaldehyde (CAS: 1899-24-7)?

5-Bromo-2-furaldehyde (CAS: 1899-24-7) is a crystalline solid with a molecular weight of approximately 169.02 g/mol. It is slightly soluble in water but easily soluble in ethanol and acetone. Chemically, it is highly reactive, particularly in nucleophilic substitution reactions. It is used as a precursor in organic synthesis and as a component in certain analytical and biological assays.

How is 5-Bromo-2-furaldehyde (CAS: 1899-24-7) typically synthesized?

5-Bromo-2-furaldehyde (CAS: 1899-24-7) is typically synthesized through a bromination reaction of 2-furaldehyde. This process often involves the use of N-bromosuccinimide (NBS) as a brominating agent, with光照引发或高温条件促进反应进行。此外，有时会使用四氯化碳作为溶剂以提高产物的选择性和产率。此反应需要精确控制反应条件，以避免副反应的发生。

What industries use 5-Bromo-2-furaldehyde (CAS: 1899-24-7)?

5-Bromo-2-furaldehyde (CAS: 1899-24-7) is used in various industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of certain drugs. It also finds applications in the production of polymers, as a component in sensors, and in the semiconductor industry for specific chemical processes. Its versatility makes it a valuable compound in organic synthesis and chemical research.

What precautions should be taken when handling 5-Bromo-2-furaldehyde (CAS: 1899-24-7)?

When handling 5-Bromo-2-furaldehyde (CAS: 1899-24-7), it is essential to use personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.