Amoxicillin EP Impurity G (Amoxicillin USP Related Compound G) | CAS No. 188112-75-6

Amoxicillin EP Impurity G (Amoxicillin USP Related Compound G)

Basic Information

CAS Number

188112-75-6

Molecular Formula

C24H26N4O7S

Molecular Weight

514.56 g/mol

AD

Basic Physical Properties

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](c3ccc(cc3)O)NC(=O)[C@@H](c4ccc(cc4)O)N)C(=O)O)C

InChI

InChI=1S/C24H26N4O7S/c1-24(2)18(23(34)35)28-21(33)17(22(28)36-24)27-20(32)16(12-5-9-14(30)10-6-12)26-19(31)15(25)11-3-7-13(29)8-4-11/h3-10,15-18,22,29-30H,25H2,1-2H3,(H,26,31)(H,27,32)(H,34,35)/t15-,16-,17-,18+,22-/m1/s1

InChIKey

IWGQIIQKNORCPQ-OSAVLUCMSA-N

LogP

0.5867999999999993

Topological Polar Surface Area

182.29 Ų

Hydrogen Bond Donor/Acceptor

7 / 11

Synonyms & References

English

  • D-hydroxyphenylglycylamoxicillin
  • p-Hydroxy-(D)-phenylglycyl Amoxicillin
  • (2S,5R,6R)-6-[[(2R)-2-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-HYDROXY-PHENYLGLYCYLAMOXICILLIN
  • (2S,5R,6R)-6-{(R)-2-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-2-(4-hydroxyphenyl)acetamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-OH-phenylglycylamoxicillin
  • AMoxicillin EP IMpurity G
  • AMoxicillin Related CoMpound G
  • Amoxicillin Related Compound G (15 mg) ((2S,5R,6R)-6-{(R)-2-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-2-(4-hydroxyphenyl)acetamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • Canagliflozin Impurity 15
  • (2S,5R,6R)-6-[[(2R)-2-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl] amino]2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane2-carboxylic acid

MDL Number

MFCD27967048

FAQ

What regulatory guidelines apply to Amoxicillin EP Impurity G (CAS: 188112-75-6)?

Amoxicillin EP Impurity G (CAS: 188112-75-6) is subject to various regulatory guidelines such as GHS for hazard classification, REACH for registration, evaluation, authorization, and restriction of chemicals in the EU, and FDA and EPA requirements for pharmaceutical and environmental safety. Compliance with these guidelines ensures safe handling and disposal.

Are there alternatives to Amoxicillin EP Impurity G (CAS: 188112-75-6) in synthesis?

Amoxicillin EP Impurity G (CAS: 188112-75-6) can be synthesized using various alternatives such as Amoxicillin USP as a parent compound. Other substitutes include using different starting materials or reagents that produce similar impurities. These alternatives can offer more cost-effective or environmentally friendly options during synthesis.

What is the market or research trend for Amoxicillin EP Impurity G (CAS: 188112-75-6)?

The market for Amoxicillin EP Impurity G (CAS: 188112-75-6) is driven by ongoing research into its pharmacokinetic properties and its role in assessing the quality of Amoxicillin products. Recent trends include increased focus on identifying and characterizing impurities to enhance drug safety and efficacy. As regulatory standards evolve, there is a growing emphasis on the analytical methods used to detect and quantify this impurity.

How should waste containing Amoxicillin EP Impurity G (CAS: 188112-75-6) be handled?

Waste containing Amoxicillin EP Impurity G (CAS: 188112-75-6) should be collected in lined drums or containers and stored in a secure, well-ventilated area. Incineration is a common disposal method, but professional waste disposal services should be utilized for handling large quantities. Environmental protection measures include proper labeling and documentation to comply with local hazardous waste regulations and minimize environmental impact.

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