2-Ethoxy Benzamidine Hydrochloride

Basic Information

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CAS Number

18637-00-8

Molecular Formula

C9H13ClN2O

Molecular Weight

200.67 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

192°C at 760 mmHg

SMILES

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CCOC1=CC=CC=C1C(=N)N.Cl

InChI

InChI=1S/C9H12N2O.ClH/c1-2-12-8-6-4-3-5-7(8)9(10)11;/h3-6H,2H2,1H3,(H3,10,11);1H

InChIKey

NGMHLSBQVIXGNZ-UHFFFAOYSA-N

LogP

1.7911700000000002

Topological Polar Surface Area

59.099999999999994 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

159

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-ethoxybenzenecarboximidamide;hydrochloride
2-Ethoxy-benzamidine hydrochloride
AKOS015914741
MFCD05663676
DTXSID00486481
NS00078204
FT-0637728
AMY40552
NGMHLSBQVIXGNZ-UHFFFAOYSA-N
A813028
18637-00-8
CS-0079901
2-ETHOXY BENZAMIDINE HCL
Benzenecarboximidamide, 2-ethoxy-, monohydrochloride
AC-4503
2-Ethoxybenzamidine HCl
2-Ethoxybenzimidamide hydrochloride
J-509303
2-ethoxybenzenecarboximidamide hydrochloride
EC 606-080-9
SCHEMBL5551
AS-10723
C93436
SY020187
2-Ethoxybenzamidine hydrochloride
2-Ethoxybenzimidamidehydrochloride
2-Ethoxybenzimidamide HCl
2-Ethoxybenzenecarboximidamide.HCl
2-Aethoxy-benzamidin,Hydrochlorid
2-Ethoxy-benzamidine
2-ETHOXY-BENZAMIDINE HCL

MDL Number

MFCD05663676

Customs Code

2925290090

FAQ

What are the physical and chemical properties of 2-Ethoxy Benzamidine Hydrochloride (CAS: 18637-00-8)?

2-Ethoxy Benzamidine Hydrochloride is a white to off-white crystalline solid. Its molecular weight is approximately 257.8 g/mol. The compound is slightly soluble in water and ethanol. It is relatively stable under normal conditions but may react with strong bases. It has a pKa of about 8.6.

How is 2-Ethoxy Benzamidine Hydrochloride (CAS: 18637-00-8) typically synthesized?

2-Ethoxy Benzamidine Hydrochloride is typically synthesized by a multi-step process involving the reaction of ethoxybenzene with benzamide followed by the addition of hydrochloric acid. The key steps include the preparation of the amide and subsequent quaternization to form the ethoxy derivative. The reaction is carried out under basic conditions and the product is isolated by recrystallization.

What industries use 2-Ethoxy Benzamidine Hydrochloride (CAS: 18637-00-8)?

2-Ethoxy Benzamidine Hydrochloride is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the production of some agricultural chemicals. Additionally, it can be used in the synthesis of other organic compounds and as a reagent in organic chemistry research.

What precautions should be taken when handling 2-Ethoxy Benzamidine Hydrochloride (CAS: 18637-00-8)?

When handling 2-Ethoxy Benzamidine Hydrochloride, it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be carefully cleaned up using appropriate procedures, and the material safety data sheet (MSDS) should be consulted for detailed guidance on safe handling and disposal.