N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine | CAS No. 185968-90-5
N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine
Basic Information
CAS Number
185968-90-5
Molecular Formula
C26H24N2O6
Molecular Weight
460.49 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- DS-14437
- CS-0149753
- (2R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(phenylmethoxycarbonylamino)propanoic acid
- Z-D-Dapa(Fmoc)-OH
- (2R)-2-{[(BENZYLOXY)CARBONYL]AMINO}-3-{[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO}PROPANOIC ACID
- N-[(Benzyloxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-D-alanine
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)carbonyl)amino)propanoic acid
- AKOS016842916
- 185968-90-5
- DTXSID00679831
- MFCD02684469
- Z-D-Dap(Fmoc)-OH
- N-alpha-BenZyloxycarbonyl-N-beta-(9-fluorenylmethyloxycarbonyl)-D-2,3-diaminopropionic acid (CbZ-D-Dap(Fmoc)-OH)
- D-Alanine,3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-N-[(phenylmethoxy)carbonyl]-
- (R)-3-(9-fluorenylmethoxycarbonylamino)-2-(benzyloxycarbonylamino)propanoic acid
- AmbotzZAA1068
- N3-Fmoc-N2-Cbz-D-2,3-diaminopropionic acid
- N-Cbz-N'-Fmoc-D-2,3-diaminopropionic acid
- Cbz-D-Dap(Fmoc)-OH
- Z-Nβ-Boc-D-2,3-diaMinopropionic acid
- N-alpha-Cbz-N-gamma-Fmoc-D-2,4-diaminopropionic acid
- (R)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(benzyloxycarbonylamino)propanoic acid
- N-ALPHA-BENZYLOXYCARBONYL-N-BETA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-2,3-DIAMINOPROPIONIC ACID
- N-ALPHA-CARBOBENZOXY-N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-D-ALPHA,BETA-DIAMINOPROPIONIC ACID
- N-ALPHA-BENZYLOXYCARBONYL-N-BETA-(9-FLUOROENYLMETHYLOXYCARBONYL)-D-2,3-DIAMINOPROPIONIC ACID
MDL Number
MFCD02684469
FAQ
What are the physical and chemical properties of N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine (CAS: 185968-90-5)?
N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine is a white crystalline solid with a molecular weight of approximately 821.47 g/mol. It is poorly soluble in water but soluble in organic solvents. Its reactivity is moderate, particularly toward nucleophilic substitution and condensation reactions. It is stable under normal conditions but should be stored in a cool, dry place away from light and moisture to prevent degradation.
How is N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine (CAS: 185968-90-5) typically synthesized?
N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine can be synthesized via multi-step procedures involving acylation and condensation reactions. The key steps include the formation of the amide bond using coupling agents like HATU or EDC, followed by protection and deprotection steps. The yield is typically around 70-80%, with high selectivity and purity.
What industries use N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine (CAS: 185968-90-5)?
N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine is primarily used in the pharmaceutical industry for the synthesis of complex peptidomimetics and bioactive compounds. It is also utilized in the polymer industry for the modification of polymer chains. Additionally, it has potential applications in the semiconductor industry for the development of organic electronic materials and sensors.
What precautions should be taken when handling N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine (CAS: 185968-90-5)?
When handling N-[(Benzyloxy)carbonyl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-D-alanine, ensure the use of appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from light and moisture. In the event of a spill, carefully clean up using appropriate procedures and consult the Safety Data Sheet (SDS) for specific guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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