1-Bromo-2-fluoro-4-nitrobenzene

Basic Information

View in Editor

CAS Number

185331-69-5

Molecular Formula

C6H3BrFNO2

Molecular Weight

220 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

88.0 to 94.0 deg-C

Boiling Point

252.9°C at 760 mmHg

Density

1.808

Flash Point

106.7°C

Refractive Index

1.579

SMILES

View in Editor

C1=CC(=C(C=C1[N+](=O)[O-])F)Br

InChI

InChI=1S/C6H3BrFNO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H

InChIKey

AZYQMHQOHNGPRR-UHFFFAOYSA-N

LogP

3.01960

Complexity

161

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

CS-W014261
MFCD05865088
AM61359
3-fluoro-4-bromonitrobenzene
AS-19434
AC-4469
1-Bromo-2-fluoro-4-nitrobenzene
AKOS005063584
AKOS005254302
SY020709
DTXSID20373682
4-Bromo-3-fluoronitrobenzene
CK2312
AZYQMHQOHNGPRR-UHFFFAOYSA-N
benzene, 1-bromo-2-fluoro-4-nitro-
FT-0659284
B3060
185331-69-5
SCHEMBL286759
EN300-115266
Benzene, 1- bromo-2-fluoro-4-nitro-
benzene,1-bromo-2-fluoro-4-nitro
1-BroMo-2-fluoro-4-nitrobenzene , 95.0%(GC)
3-Fluoro-4-bromonitrobenzene

MDL Number

MFCD05865088

FAQ

What are the physical and chemical properties of 1-Bromo-2-fluoro-4-nitrobenzene (CAS: 185331-69-5)?

1-Bromo-2-fluoro-4-nitrobenzene is a crystalline solid with a molecular weight of 241.04 g/mol. It is sparingly soluble in water but soluble in common organic solvents such as ethanol and dichloromethane. Chemically, it is reactive towards nucleophiles, particularly in substitution reactions, and can be used as an electrophilic aromatic substitution reagent.

How is 1-Bromo-2-fluoro-4-nitrobenzene (CAS: 185331-69-5) typically synthesized?

1-Bromo-2-fluoro-4-nitrobenzene can be synthesized via bromination of 2-fluoro-4-nitrobenzene using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction typically proceeds with high selectivity and moderate yield, making it a useful intermediate in organic synthesis.

What industries use 1-Bromo-2-fluoro-4-nitrobenzene (CAS: 185331-69-5)?

1-Bromo-2-fluoro-4-nitrobenzene is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the polymer industry for the development of new materials. It may also find applications in the production of sensors and semiconductors due to its reactivity and stability.

What precautions should be taken when handling 1-Bromo-2-fluoro-4-nitrobenzene (CAS: 185331-69-5)?

When handling 1-Bromo-2-fluoro-4-nitrobenzene, operators should wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area, and work should be conducted in a fume hood. In the event of a spill, clean up using appropriate absorbent materials and follow the Material Safety Data Sheet (MSDS) for disposal instructions.