1-Bromo-2-fluoro-4-nitrobenzene(CAS: 185331-69-5)

1-Bromo-2-fluoro-4-nitrobenzene is a crystalline solid with a molecular weight of 241.04 g/mol. It is sparingly soluble in water but soluble in common organic solvents such as ethanol and dichloromethane. Chemically, it is reactive towards nucleophiles, particularly in substitution reactions, and can be used as an electrophilic aromatic substitution reagent.

1-Bromo-2-fluoro-4-nitrobenzene can be synthesized via bromination of 2-fluoro-4-nitrobenzene using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction typically proceeds with high selectivity and moderate yield, making it a useful intermediate in organic synthesis.

1-Bromo-2-fluoro-4-nitrobenzene is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the polymer industry for the development of new materials. It may also find applications in the production of sensors and semiconductors due to its reactivity and stability.

When handling 1-Bromo-2-fluoro-4-nitrobenzene, operators should wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area, and work should be conducted in a fume hood. In the event of a spill, clean up using appropriate absorbent materials and follow the Material Safety Data Sheet (MSDS) for disposal instructions.