Acotiamide | CAS No. 185106-16-5

Acotiamide

Basic Information

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CAS Number

185106-16-5

Molecular Formula

C21H30N4O5S

Molecular Weight

450.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Insuluble (1.7E-3 g/L) (25 ºC),

SMILES

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CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(C)C

InChI

InChI=1S/C21H30N4O5S/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27)

InChIKey

TWHZNAUBXFZMCA-UHFFFAOYSA-N

LogP

2.966800000000001

Topological Polar Surface Area

113.02000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

586

Synonyms & References

English

AcotiaMide
N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide
MZ-338
UNII-D42OWK5383
N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide
Acofide
ACOTIAMIDUM
N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride
AC-27642
4-THIAZOLECARBOXAMIDE, N-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-2-((2-HYDROXY-4,5-DIMETHOXYBENZOYL)AMINO)-
SCHEMBL1043131
NCGC00506872-01
N-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-2-((2-HYDROXY-4,5-DIMETHOXYBENZOYL)AMINO)THIAZOLE-4-CARBOXAMIDE
DA-50177
Q4674598
CHEBI:34523
ACOTIAMIDE [WHO-DD]
AKOS025401963
Acotiamide [INN]
185106-16-5
NS00068788
D42OWK5383
CCG-269239
C14127
Acotiamide; MZ-338; UNII-D42OWK5383;
DB12482
SB19646
A899477
ACOTIAMIDE [MI]
N-(2-(Bis(1-methylethyl)amino)ethyl)-2-((2-hydroxy-4,5-dimethoxybenzoyl)amino)thiazol-4-carboxamide
Acotiamide?

MDL Number

MFCD00953661

FAQ

What regulatory guidelines apply to Acotiamide (CAS: 185106-16-5)?

Acotiamide (CAS: 185106-16-5) is subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes hazard communication, physical hazards, health hazards, and environmental hazards. Additionally, it falls under the European Union's Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation and may be regulated by the U.S. Food and Drug Administration (FDA) or Environmental Protection Agency (EPA) depending on its intended use.

Are there alternatives to Acotiamide (CAS: 185106-16-5) in synthesis?

There are several alternatives to Acotiamide (CAS: 185106-16-5) that may be used in synthesis, including analogs like Acotiamide derivatives and other compounds with similar pharmacological profiles. Common alternative reagents include various amides, esters, and other functional groups that can serve as precursors in synthetic routes.

What is the market or research trend for Acotiamide (CAS: 185106-16-5)?

The market and research for Acotiamide (CAS: 185106-16-5) is primarily focused on its use as an anticholinergic agent, particularly for the treatment of gastroesophageal reflux disease (GERD). Research trends include investigating its efficacy in other indications and exploring its potential as an adjuvant therapy. Market trends show increasing interest in gastrointestinal health products, which supports the ongoing development and clinical evaluation of Acotiamide.

How should waste containing Acotiamide (CAS: 185106-16-5) be handled?

Waste containing Acotiamide (CAS: 185106-16-5) should be collected in sealed containers and disposed of in accordance with local regulations. Professional waste disposal services are recommended to ensure safe and environmentally responsible handling. Precautions include wearing appropriate personal protective equipment (PPE) and following safety guidelines to prevent exposure and contamination. Incineration or other specialized disposal methods may be necessary depending on the waste's characteristics and local environmental regulations.