4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol | CAS No. 185066-37-9

4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol

Basic Information

CAS Number

185066-37-9

Molecular Formula

C31H39NO2

Molecular Weight

457.66 g/mol

AD

Basic Physical Properties

Boiling Point

618.6±55.0 °C at 760 mmHg

Density

1.1±0.1 g/cm3

Flash Point

305.6±30.2 °C

Vapor Pressure

0.0±1.9 mmHg at 25°C

CC(C)c1ccc(cc1)C(CCCN2CCC(CC2)C(c3ccccc3)(c4ccccc4)O)O

InChI

InChI=1S/C31H39NO2/c1-24(2)25-15-17-26(18-16-25)30(33)14-9-21-32-22-19-29(20-23-32)31(34,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-13,15-18,24,29-30,33-34H,9,14,19-23H2,1-2H3

InChIKey

FZSQPQGERLSIOR-UHFFFAOYSA-N

LogP

6.271700000000009

Topological Polar Surface Area

43.7 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

546

Synonyms & References

English

  • 1-Piperidinebutanol, 4-(hydroxydiphenylmethyl)-a-[4-(1-methylethyl)phenyl]-
  • Decarboxy Fexofenadine
  • (1RS)-4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol
  • Fexofenadine EP Impurity C
  • Fexofenadine hydrochloride impurity C (EP)
  • 4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-1-(4-propan-2-ylphenyl)butan-1-ol
  • 4-[4-(Hydroxydiphenylmethyl)piperidinyl]-1-(p-isopropylphenyl)butane-1-ol hydrochloride
  • Oprea1_743778
  • 4-{4-[HYDROXY(DIPHENYL)METHYL]-1-PIPERIDINYL}-1-(4-ISOPROPYLPHENYL)-1-BUTANOL
  • 4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]-1-(4-isopropylphenyl)butan-1-ol
  • 4-(4'-(Hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-iso-propylphenyl)butan-1-ol
  • 4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-isopropylphenyl)butan-1-ol

MDL Number

MFCD00953788

FAQ

What regulatory guidelines apply to 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9)?

The compound 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), this compound may be classified as a skin irritant and should be labeled accordingly. It is also regulated under REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in the EU, requiring comprehensive safety data sheets (SDS) and registration if used in quantities above the threshold. FDA and EPA may have specific requirements for its use in pharmaceuticals and environmental safety, respectively.

Are there alternatives to 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) in synthesis?

Alternatives to 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) in synthesis include related analogs such as other piperidine derivatives with similar functional groups. Common alternative reagents include various amines and alcohols that can be used as building blocks to synthesize similar compounds. These alternatives can offer similar properties or improved stability and solubility for different applications.

What is the market or research trend for 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9)?

The market and research trend for 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) focuses on its potential use in pharmaceuticals and cosmetics due to its unique chemical structure. Research is ongoing to explore its biological activities, such as its potential as an analgesic or anti-inflammatory agent. Market trends indicate increasing interest in developing novel compounds with similar properties for therapeutic applications, driven by advancements in drug discovery and personalized medicine.

How should waste containing 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) be handled?

Waste containing 4-{4-[Hydroxy(diphenyl)methyl]-1-piperidinyl}-1-(4-isopropylphenyl)-1-butanol (CAS: 185066-37-9) should be managed responsibly to minimize environmental impact. Waste liquid should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration may be an option, but should be conducted in a controlled environment to prevent emissions. Proper waste management practices should include the use of safe handling procedures, personal protective equipment, and adherence to local, national, and international regulations governing hazardous waste disposal.

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