2-Methyl-4-pyridinamine

Basic Information

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CAS Number

18437-58-6

Molecular Formula

C6H8N2

Molecular Weight

108.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

No data available

Melting Point

93-97 °C

Boiling Point

143°C/9mmHg

Density

1.0680

Flash Point

126.9℃

Solubility

Soluble in methanol.

SMILES

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CC1=NC=CC(=C1)N

InChI

InChI=1S/C6H8N2/c1-5-4-6(7)2-3-8-5/h2-4H,1H3,(H2,7,8)

InChIKey

GNCLPNMQEGMNTG-UHFFFAOYSA-N

LogP

0.9722200000000001

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

72.9

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class TOXIC Class TOXIC

Synonyms & References

English

BCP22105
4-Amino-2-picoline
2-methylpyridin-4-ylamine
4-Amino-2-methylpyridine, 97%
18437-58-6
4-pyridinamine, 2-methyl-
NoName_3009
4-Amino-2-methylpyridine
CS-D0974
FT-0637695
MFCD00186509
CL0056
2-methyl-4-aminopyridine
Q-101508
GNCLPNMQEGMNTG-UHFFFAOYSA-N
4-amino-methylpyridine
2-methyl-4-pyridinamine
4-amino-2-methyl-pyridine
PS-9288
SB10589
2-methylpyridine-4-amine
AC-3013
SCHEMBL266271
HMS1716O22
SY003568
2-Methyl-pyridin-4-ylamine
DTXSID90902504
4-Amino-2-methylpyridine (4-Amino-2-picoline)
2-methylpyridin-4-amine
2-methylpyridin-4-amin
AKOS000271091

MDL Number

MFCD00186509

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-4-pyridinamine (CAS: 18437-58-6)?

2-Methyl-4-pyridinamine is a crystalline solid with a molecular weight of approximately 113.15 g/mol. It is slightly soluble in water and ethanol. Chemically, it is moderately reactive towards acids and bases, making it prone to hydrolysis under certain conditions. It is stable under normal storage conditions but may degrade at high temperatures or in strong oxidizing environments.

How is 2-Methyl-4-pyridinamine (CAS: 18437-58-6) typically synthesized?

2-Methyl-4-pyridinamine can be synthesized via the amination of 2-methyl-4-nitropyridine with ammonia in the presence of a catalyst such as Raney nickel. The process typically yields high purity material with good selectivity and yield, making it suitable for commercial production.

What industries use 2-Methyl-4-pyridinamine (CAS: 18437-58-6)?

2-Methyl-4-pyridinamine is primarily used in the pharmaceutical industry as a precursor for drugs, and also in the polymer industry for the synthesis of advanced materials. It also finds applications in the production of sensors and semiconductors due to its chemical properties.

What precautions should be taken when handling 2-Methyl-4-pyridinamine (CAS: 18437-58-6)?

When handling 2-Methyl-4-pyridinamine, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with caution, using appropriate cleanup materials, and the area should be thoroughly cleaned. Refer to the Safety Data Sheet (SDS) for specific guidelines on handling and storage.