4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide | CAS No. 184007-95-2

4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

Basic Information

CAS Number

184007-95-2

Molecular Formula

C17H14F3N3O2S

Molecular Weight

381.38 g/mol

AD

Basic Physical Properties

Melting Point

157-159 deg C

Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F

InChI

InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)

InChIKey

RZEKVGVHFLEQIL-UHFFFAOYSA-N

LogP

3.5139200000000015

Topological Polar Surface Area

77.98 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

577

Synonyms & References

English

  • CELECOXIB
  • Ccris 8679
  • Celecoxib [old rn]

FAQ

What is 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (CAS: 184007-95-2)?

4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide is a complex organic compound with a molecular structure featuring a benzene ring, a sulfonamide group, and a pyrazole ring with trifluoromethyl and methyl substituents. It is a white or off-white crystalline solid with a specific melting point and solubility in certain organic solvents.

What are the main uses of 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (CAS: 184007-95-2)?

This compound is primarily used in the pharmaceutical industry as an intermediate for the synthesis of drug candidates. It may also find applications in research for its potential biological activities, although specific uses are not well-documented in the public domain.

Is 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (CAS: 184007-95-2) safe?

The safety of 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide depends on the context of use. It should be handled with caution due to its chemical structure. Protective measures, including appropriate personal protective equipment (PPE) and adherence to safety guidelines, are necessary to prevent exposure and ensure safe handling.

How should 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (CAS: 184007-95-2) be stored?

It should be stored in a cool, dry place, away from direct sunlight and sources of heat. The compound should be kept in a tightly sealed container to protect it from moisture and light. Proper storage conditions are essential to maintain its stability and prevent degradation.

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