2-Chloro-7H-purin-6-amine

Basic Information

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CAS Number

1839-18-5

Molecular Formula

C5H4ClN5

Molecular Weight

169.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

384-389 °C

Boiling Point

315.2°C at 760 mmHg

Refractive Index

1.6110 (estimate)

SMILES

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C1=NC2=NC(=NC(=C2N1)N)Cl

InChI

InChI=1S/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)

InChIKey

HBJGQJWNMZDFKL-UHFFFAOYSA-N

LogP

0.5884999999999998

Topological Polar Surface Area

80.47999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

154

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

SY035219
2-Chloro-9H-purin-6-ylamine
2-chloro-1H-purine-6-amine
AC-1007
1839-18-5
CHEMBL134192
2-Chloroadenine, 97%
HBJGQJWNMZDFKL-UHFFFAOYSA-N
AKOS028109325
2-chloro-7H-purin-6-amine
Q-200260
AKOS005257637
FT-0601064
Cladribine impurity C, European Pharmacopoeia (EP) Reference Standard
BDBM50056180
2-chloro-adenine
NSC 7362
SQ 22982
Z1741971500
2-Chloro-6-aminopurine
CS-W017715
C2575
2-chloradenin
2-Chloroadenine
PS-4933
A05OL9V6OM
AKOS006281627
6-Amino-2-chloropurine
SCHEMBL29745
2-chloro-9H-purin-6-amine
HY-W016999

MDL Number

MFCD00037925

Customs Code

2933990090

FAQ

What is 2-Chloro-7H-purin-6-amine (CAS: 1839-18-5)?

2-Chloro-7H-purin-6-amine, also known as 2-Chloropurin-6-amine, is a purine derivative with the chemical formula C5H4N3Cl. It has a molecular weight of approximately 142.57 g/mol. This compound is characterized by its purine ring structure, which is a crucial component in nucleic acids and plays a significant role in biological processes.

What are the main uses of 2-Chloro-7H-purin-6-amine (CAS: 1839-18-5)?

2-Chloro-7H-purin-6-amine is mainly used in pharmaceutical research and development, particularly in the synthesis of various purine analogs for antiviral and antitumor drugs. It serves as a key intermediate in the production of chemotherapeutic agents and as a tool compound in medicinal chemistry studies.

Is 2-Chloro-7H-purin-6-amine (CAS: 1839-18-5) safe?

2-Chloro-7H-purin-6-amine, like many chemical compounds, requires careful handling due to its potential for skin and eye irritation. It is important to follow appropriate safety guidelines, such as using personal protective equipment (PPE) and ensuring proper ventilation. Storage should be in a cool, dry place away from direct sunlight. Compliance with local safety standards and regulations is essential for safe handling.

How should 2-Chloro-7H-purin-6-amine (CAS: 1839-18-5) be stored?

2-Chloro-7H-purin-6-amine should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a sealed, airtight container to prevent moisture and contamination. Proper labeling is crucial to ensure that only authorized personnel handle the compound. It is advisable to maintain a temperature range of 15-25°C (59-77°F).