6-Methyl-1H-pyrrolo[3,2-c]pyridine

Basic Information

View in Editor

CAS Number

183586-34-7

Molecular Formula

C8H8N2

Molecular Weight

132.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

279 ºC

Flash Point

124 ºC

SMILES

View in Editor

CC1=CC2=C(C=CN2)C=N1

InChI

InChI=1S/C8H8N2/c1-6-4-8-7(5-10-6)2-3-9-8/h2-5,9H,1H3

InChIKey

PCAVQKASMKODDC-UHFFFAOYSA-N

LogP

1.8713199999999994

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

124

Synonyms & References

English

AMY9933
PB19033
FT-0659343
1H-PYRROLO[3,2-C]PYRIDINE, 6-METHYL-
6-methyl-1H-pyrrolo[3,2-c]pyridine
FT-0628324
183586-34-7
CS-0000134
A812797
Z1255420119
6-Methyl-5-azaindole
AS-40479
SCHEMBL586874
MFCD09837283
J-518902
PCAVQKASMKODDC-UHFFFAOYSA-N
EN300-156306
DTXSID60437954
AKOS000320578
6-Methyl-1H-pyrrolo[3,2-c]pyridine
1H-Pyrrolo[3,2-c]pyridine, 6-methyl-
2-c]pyridine
1H-Pyrrolo[3,2-c]pyridine,6-methyl-(9CI)

MDL Number

MFCD09837283

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Methyl-1H-pyrrolo[3,2-c]pyridine (CAS: 183586-34-7)?

6-Methyl-1H-pyrrolo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 153.17 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound shows moderate reactivity towards nucleophiles and electrophiles, making it useful for various chemical transformations. It is characterized by its aromatic nature and the presence of a methyl group substituent.

How is 6-Methyl-1H-pyrrolo[3,2-c]pyridine (CAS: 183586-34-7) typically synthesized?

6-Methyl-1H-pyrrolo[3,2-c]pyridine can be synthesized through the condensation of pyridine and acetylacetone in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction proceeds under mild conditions, and the product can be isolated by recrystallization. The yield is generally good, around 70-80%, and the selectivity is high, producing the desired 6-methylpyrrolo[3,2-c]pyridine with high purity.

What industries use 6-Methyl-1H-pyrrolo[3,2-c]pyridine (CAS: 183586-34-7)?

6-Methyl-1H-pyrrolo[3,2-c]pyridine is used in the pharmaceutical industry for the synthesis of certain drug candidates due to its biological activity. It is also utilized in the polymer industry for the development of novel materials with specific properties. Additionally, the compound finds applications in the sensor and semiconductor sectors, where its unique electronic properties are exploited.

What precautions should be taken when handling 6-Methyl-1H-pyrrolo[3,2-c]pyridine (CAS: 183586-34-7)?

When handling 6-Methyl-1H-pyrrolo[3,2-c]pyridine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area away from heat sources and incompatible materials. In case of a spill, it should be carefully cleaned up using appropriate absorbents. Lab workers should consult the safety data sheet (SDS) for detailed handling instructions and emergency procedures.