Erlotinib EP Impurity H HCl | CAS No. 183320-19-6

Erlotinib EP Impurity H HCl

Basic Information

CAS Number

183320-19-6

Molecular Formula

C21H21Cl2N3O3

Molecular Weight

434.32 g/mol

AD

Basic Physical Properties

COCCOc1cc2c(ncnc2cc1OCCCl)Nc1cccc(c1)C#C.Cl

InChI

InChI=1S/C20H22ClN3O3/c1-14-4-3-5-15(10-14)24-20-16-11-18(27-9-8-25-2)19(26-7-6-21)12-17(16)22-13-23-20/h3-5,10-13H,6-9H2,1-2H3,(H,22,23,24)

InChIKey

XCZBBJCKNLHDMA-UHFFFAOYSA-N

LogP

4.324620000000004

Topological Polar Surface Area

65.5 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Synonyms & References

English

  • 7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride
  • 7-(2-chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)quinazolin-4-amine
  • hydrochloride (1:1)

FAQ

What regulatory guidelines apply to Erlotinib EP Impurity H HCl (CAS: 183320-19-6)?

Erlotinib EP Impurity H HCl (CAS: 183320-19-6) is subject to various regulatory guidelines. It must comply with the Globally Harmonized System (GHS) for Classification and Labeling of Chemicals, REACH regulations in the European Union, and FDA and EPA guidelines in the United States. Manufacturers should ensure proper documentation and reporting for safety data sheets (SDS) and material safety data sheets (MSDS).

Are there alternatives to Erlotinib EP Impurity H HCl (CAS: 183320-19-6) in synthesis?

While Erlotinib EP Impurity H HCl (CAS: 183320-19-6) is an important impurity in synthesis, alternatives include using higher purity Erlotinib HCl or alternative impurities. These can serve as safer substitutes, reducing the risk of impurity accumulation in the final product.

What is the market or research trend for Erlotinib EP Impurity H HCl (CAS: 183320-19-6)?

The market for Erlotinib EP Impurity H HCl (CAS: 183320-19-6) is closely tied to the broader market for Erlotinib HCl. Recent trends indicate a growing demand for Erlotinib-related products in oncology research and clinical trials. Emerging research is focusing on impurity profiling and control to ensure drug efficacy and safety.

How should waste containing Erlotinib EP Impurity H HCl (CAS: 183320-19-6) be handled?

Waste containing Erlotinib EP Impurity H HCl (CAS: 183320-19-6) should be handled according to local and international hazardous waste regulations. Collection should be done in appropriate containers, and the waste should be incinerated or disposed of by a professional waste disposal service. Environmental precautions include ensuring no leakage or spillage to prevent contamination. Proper documentation and reporting are required for disposal and transport.

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