5-(1-Piperazinyl)-1-benzofuran-2-carboxamide

Basic Information

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CAS Number

183288-46-2

Molecular Formula

C13H15N3O2

Molecular Weight

245.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

250-255°C

Boiling Point

505.319°C at 760 mmHg

SMILES

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NC(=O)c1oc2c(c1)cc(cc2)N1CCNCC1

InChI

InChI=1S/C13H15N3O2/c14-13(17)12-8-9-7-10(1-2-11(9)18-12)16-5-3-15-4-6-16/h1-2,7-8,15H,3-6H2,(H2,14,17)

InChIKey

LLRGOAFFRRUFBM-UHFFFAOYSA-N

LogP

0.9412999999999998

Topological Polar Surface Area

71.5 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

317

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-(Piperazin-1-yl)benzofuran-2-carboxamide
1-(2-Amicarbonylbenzofuran-5-yl)piperazine
1-(2-aminocarbonylbenzofuran-5-yl)piperazine
5-(1-piperazinyl)-2-Benzofurancarboxamide
5-(1-Piperazinyl)benzofuran-2-carboxamide
5-(Piperazin-1-yl)be
Vilazodone Intermediate 4
Vilazodone INT 4
1-(2-AMinocarbonylbenzofuran-5-yl)
5-(1-Piperazinyl)benzofuran-2-carboxamid
5-(Piperazine-1-yl) benzofuran-2-carboxamide
5‐(1‐Piperazinyl)‐1‐benzofuran‐2‐carboxamide
5-Piperazin-1-yl-benzofuran-2-carboxylic acid aMide
2-Benzofurancarboxamide, 5-(1-piperazinyl)-
5-piperazin-1-ylbenzofuran-2-carboxamide
BEN783
LLRGOAFFRRUFBM-UHFFFAOYSA-N
BCP06221
RL02335
T

MDL Number

MFCD20486139

FAQ

What regulatory guidelines apply to 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide (CAS: 183288-46-2)?

5-(1-Piperazinyl)-1-benzofuran-2-carboxamide (CAS: 183288-46-2) is subject to regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations, and FDA/EPA requirements. Specific attention should be given to its storage, handling, and disposal to comply with these regulations.

Are there alternatives to 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide in synthesis?

There are several alternatives to 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide in synthesis, including isomers and analogs such as 5-(2-pyrrolidinyl)-1-benzofuran-2-carboxamide and related compounds. These alternatives can serve similar biological functions and may offer different advantages in terms of solubility, stability, or pharmacokinetics.

What is the market or research trend for 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide?

The market for 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide (CAS: 183288-46-2) is driven by its potential applications in medicinal chemistry and drug discovery. Recent research trends focus on its use as a lead compound for developing new therapeutic agents, particularly in the treatment of neurological disorders. Market trends indicate increasing interest and investment in this area.

How should waste containing 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide be handled?

Waste containing 5-(1-Piperazinyl)-1-benzofuran-2-carboxamide (CAS: 183288-46-2) should be collected in suitable containers and stored under appropriate conditions to prevent environmental contamination. Incineration or professional waste disposal services should be used for final disposal. Environmental protection precautions should be taken to ensure compliance with local regulations and minimize environmental impact.