4-Hydroxy-2-methoxybenzaldehyde

Basic Information

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CAS Number

18278-34-7

Molecular Formula

C8H8O3

Molecular Weight

152.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

156.0 to 160.0 deg-C

Boiling Point

312.9℃ at 760 mmHg

Flash Point

132.3 °C

Refractive Index

1.4447 (estimate)

SMILES

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COC1=C(C=CC(=C1)O)C=O

InChI

InChI=1S/C8H8O3/c1-11-8-4-7(10)3-2-6(8)5-9/h2-5,10H,1H3

InChIKey

WBIZZNFQJPOKDK-UHFFFAOYSA-N

LogP

1.2133

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

135

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

BB 0260623
A812725
SY041931
2-methoxy-4-hydroxybenzaldehyde
HMS2764H22
H1191
Q-200476
AB00651417-06
MFCD00051964
PS-3220
SMR000370826
p-hydroxy-o-methoxybenzaldehyde
4-Hydroxy-o-anisaldehyde
4-Hydroxyl-2-methoxyl benzaldehyde
2-methoxy-4-hydroxy-benzaldehyde
FT-0618628
4-Hydroxy-2-methoxybenzaldehyde #
EN300-24459
BP-13155
18278-34-7
AKOS001284090
ArgoGel(TM)-MB-CHO, 120-230 mum particle size
4-Hydroxy-2-methoxybenzaldehyde
4-Hydroxy-2-methoxybenaldehyde
CHEMBL1309669
AM808233
Benzaldehyde, 4-hydroxy-2-methoxy-
4-Hydroxy-2-methoxybenzaldehyde, >=98.0% (HPLC)
AC-19108
SCHEMBL37462
MLS000760729

MDL Number

MFCD00051964

FAQ

What regulatory guidelines apply to 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7)?

4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a category 3 skin sensitiser. It is also subject to the European Union’s Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulations and the U.S. EPA's Toxic Substances Control Act (TSCA). FDA may also require specific safety data for products containing this compound.

Are there alternatives to 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7) in synthesis?

Common alternatives to 4-Hydroxy-2-methoxybenzaldehyde include other aromatic aldehydes such as vanillin and benzaldehyde. Isomers like 2-methoxy-4-hydroxybenzaldehyde may also be used as substitutes depending on the specific application requirements. Other reagents like hydroxymethylbenzaldehyde can also be considered in alternative syntheses.

What is the market or research trend for 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7)?

The market for 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7) is driven by its use in fragrance and flavor industries. Recent research trends focus on its potential as a natural alternative to synthetic fragrances, with increasing demand for eco-friendly and sustainable products. Additionally, its use in pharmaceuticals and cosmetics is expanding, driven by its antioxidant and anti-inflammatory properties.

How should waste containing 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7) be handled?

Waste containing 4-Hydroxy-2-methoxybenzaldehyde (CAS: 18278-34-7) should be collected in sealed, leak-proof containers and disposed of according to local hazardous waste regulations. Incineration is an effective method for disposal, but professional waste disposal services are recommended to ensure compliance with environmental protection standards. Proper labeling and documentation of waste must be maintained to prevent accidental exposure and ensure safe handling.