7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one | CAS No. 1825352-65-5
7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Basic Information
CAS Number
1825352-65-5
Molecular Formula
C22H23N7O
Molecular Weight
401.47 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Risdiplam
- RG7916
- RO7034067
- 76RS4S2ET1
- 2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
- 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
- Evrysdi
- Risdiplam [INN]
- Evrysdi (TN)
- Risdiplam [USAN]
- Risdiplam; RG7916
- Risdiplam [USAN:INN]
- Risdiplam (JAN/USAN/INN)
- GTPL11170
- AMY23728
- WHO
MDL Number
MFCD31657372
FAQ
What are the physical and chemical properties of 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS: 1825352-65-5)?
The compound has a crystalline form with a molecular weight of approximately 491.6 g/mol. It is slightly soluble in common organic solvents like DMSO and ethanol. Chemically, it shows moderate reactivity towards nucleophiles and is stable under acidic and basic conditions. It can be used as a precursor in various chemical transformations.
How is 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS: 1825352-65-5) typically synthesized?
This compound is synthesized through a multi-step process involving condensation reactions and ring formations. Key synthetic intermediates include a 2,8-dimethylimidazo[1,2-b]pyridazin-6-yl derivative and a 4,7-diazaspiro[2.5]oct-7-yl moiety. The final product is obtained with good yield and selectivity via optimized reaction conditions and catalysts.
What industries use 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS: 1825352-65-5)?
This compound is primarily used in the pharmaceutical industry for the development of novel drug candidates. It also has potential applications in the polymer industry for specific polymer modifications and in the sensor industry for the development of new sensing materials. Its unique chemical structure makes it suitable for various high-tech applications.
What precautions should be taken when handling 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS: 1825352-65-5)?
Proper personal protective equipment (PPE) should be worn, including gloves, lab coat, and safety glasses. The compound should be handled in a fume hood to minimize inhalation risk. In case of spills, they should be carefully cleaned up using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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