6-Methyl-2-pyridinamine

Basic Information

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CAS Number

1824-81-3

Molecular Formula

C6H8N2

Molecular Weight

108.14 g/mol

EINECS

217-360-1

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

40-44 °C

Boiling Point

208-209 °C

Density

1.0275 (estimate)

Water Solubility

very faint turbidity

Flash Point

218 °F

Refractive Index

1.5560 (estimate)

SMILES

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Cc1cccc(N)n1

InChI

InChI=1S/C6H8N2/c1-5-3-2-4-6(7)8-5/h2-4H,1H3,(H2,7,8)

InChIKey

QUXLCYFNVNNRBE-UHFFFAOYSA-N

LogP

0.9722199999999999

pKa

pK1: 7.41(+1) (25°C)

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

72.9

Safety Information

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GHS Hazard Pictograms

H301

H310

H315

H319

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Hygroscopic

Synonyms & References

English

2-amino-6-methyl-pyridin
2-Picoline, 6-amino-
2-Pyridinamine,6-methyl-
6-Amino-2-methylpyridine
6-Methyl-2-aminopyridine
2-AMINO-6-METHYL PYRIDINE 6-METHYLPYRIDIN-2-YLAMINE
2-AMINO-6-METHYLPYRIDINE (2-AMINO-6-PICOLINE)
2-Amino-6-picoline ,98%
2-Amino-6-picoline
6-methyl-2-pyridinamin
6-Methyl-2-pyridinamine
2-Amino-6-methylpyridine
6-methylpyridin-2-amine
2-amino-6-Me-pyridine
2-amino-6-methyl-pyridine
2-Picoline,6-amino
2-Pyridinamine,6-methyl
6-Amino-2-picoline
6-MePy-2-NH2
6-Methyl-2-pyridylamine
6-Methyl-pyridin-2-ylamine

MDL Number

MFCD00006331

EC Number

217-360-1

Customs Code

29333999

FAQ

What is 6-Methyl-2-pyridinamine (CAS: 1824-81-3)?

6-Methyl-2-pyridinamine, also known as 2-pyridinylmethylamine, is a heterocyclic organic compound with the chemical formula C6H7N2. It features a pyridine ring substituted with a methyl group at position 6 and an amino group at position 2. This compound is commonly used in pharmaceutical and chemical synthesis due to its structural versatility and reactivity. Its properties include solubility in polar solvents and stability under normal conditions.

What are the main uses of 6-Methyl-2-pyridinamine (CAS: 1824-81-3)?

6-Methyl-2-pyridinamine is primarily utilized as a pharmaceutical intermediate in the synthesis of antifungal and antibiotic drugs. It also finds applications in industrial chemistry for producing dyes, pesticides, and other organic compounds. In research settings, it serves as a building block for developing new materials and chemical entities. Its unique molecular structure makes it valuable in medicinal chemistry and functional chemical synthesis.

Is 6-Methyl-2-pyridinamine (CAS: 1824-81-3) safe?

6-Methyl-2-pyridinamine is generally considered safe when handled properly, but it may cause mild irritation to skin, eyes, or respiratory systems. Safety data sheets (SDS) recommend using appropriate personal protective equipment (PPE) and ensuring proper ventilation. While it is not classified as highly toxic, adherence to standard chemical safety protocols is essential to minimize risks during handling and storage.

How should 6-Methyl-2-pyridinamine (CAS: 1824-81-3) be stored?

6-Methyl-2-pyridinamine should be stored in a cool, dry, and dark environment to maintain stability. It is best kept in airtight, moisture-proof containers made of glass or polyethylene. Storage conditions should avoid exposure to light and humidity, with a recommended temperature range of 2-8°C. Always ensure proper labeling and follow safety standards for chemical storage to prevent degradation or contamination.