1H-Pyrazol-5-amine

Basic Information

View in Editor

CAS Number

1820-80-0

Molecular Formula

C3H5N3

Molecular Weight

83.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

34-37 °C

Boiling Point

218 °C/122 mmHg

Refractive Index

1.5060 (estimate)

SMILES

View in Editor

C1=C(NN=C1)N

InChI

InChI=1S/C3H5N3/c4-3-1-2-5-6-3/h1-2H,(H3,4,5,6)

InChIKey

JVVRJMXHNUAPHW-UHFFFAOYSA-N

LogP

-0.008100000000000107

Topological Polar Surface Area

54.7 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

45.3

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H314

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air & Light Sensitive

Synonyms & References

English

BB 0219775
BTB7URA7K8
CS-D1141
1H-5-pyrazolamine
1h-pyrazole-imine
1H-pyrazol-5-amine
3-Aminopyrazole
5-amino-pyrazole
J-504847
1H-Pyrazole-5-amine
EN300-27598
Pyrazol-3-ylamine
NSC 76122
1H-pyrazole-3-amine
A15324
AKOS002657057
Q-101973
BCP27171
PB32063
114024-26-9
3-AMINOPYRAZOL
amino pyrazole
1H-Pyrazol-3-amine
InChI=1/C3H5N3/c4-3-1-2-5-6-3/h1-2H,(H3,4,5,6
MFCD00005236
aminopyrazole
FT-0600489
Q27453670
EINECS 217-338-1
1820-80-0
FT-0649846

MDL Number

MFCD00005236

Customs Code

2933199090

FAQ

What is 1H-Pyrazol-5-amine (CAS: 1820-80-0)?

1H-Pyrazol-5-amine (CAS: 1820-80-0) is a heterocyclic organic compound with the chemical formula C3H4N2. It features a pyrazole ring with an amino group at the 5th position, making it a key intermediate in pharmaceutical and chemical synthesis. The compound is typically a white solid with moderate solubility in water and organic solvents, and it exhibits basic properties due to the amino functionality.

What are the main uses of 1H-Pyrazol-5-amine (CAS: 1820-80-0)?

1H-Pyrazol-5-amine (CAS: 1820-80-0) is widely used in pharmaceuticals as a building block for drugs targeting neurological disorders and cancer. It also serves in agrochemicals, materials science, and research for developing bioactive compounds. Its versatility in chemical reactions makes it valuable for synthesizing derivatives with applications in medicinal chemistry and industrial processes.

Is 1H-Pyrazol-5-amine (CAS: 1820-80-0) safe?

1H-Pyrazol-5-amine (CAS: 1820-80-0) is generally considered safe when handled properly, but it may cause irritation to the skin, eyes, or respiratory system. Safety data sheets (SDS) recommend using protective equipment like gloves and goggles, and ensuring adequate ventilation. It is classified as a hazardous substance under OSHA and EPA guidelines, requiring careful adherence to handling protocols to minimize risks.

How should 1H-Pyrazol-5-amine (CAS: 1820-80-0) be stored?

1H-Pyrazol-5-amine (CAS: 1820-80-0) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It requires a sealed container to prevent moisture absorption and contamination. Avoid exposure to light and air to maintain stability, and ensure storage in a well-ventilated area to reduce potential hazards from volatile components.