(2,6-Dimethyl-4-pyridinyl)methanol

Basic Information

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CAS Number

18088-01-2

Molecular Formula

C8H11NO

Molecular Weight

137.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

102-103 ºC

Boiling Point

242.7±35.0 ºC (760 Torr),

Flash Point

100.6±25.9 ºC,

SMILES

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CC1=CC(=CC(=N1)C)CO

InChI

InChI=1S/C8H11NO/c1-6-3-8(5-10)4-7(2)9-6/h3-4,10H,5H2,1-2H3

InChIKey

DLDGHMPQNVTNRC-UHFFFAOYSA-N

LogP

1.19074

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

95.4

Synonyms & References

English

(2,6-dimethyl-4-pyridyl)methanol
AKOS005255193
FT-0685540
(2,6-Dimethyl-pyridin-4-yl)-methanol
(2,6-dimethylpyridin-4-yl)methanol
2,6-dimethyl-4-pyridinemethanol
A812568
4-Pyridinemethanol,2,6-dimethyl-
MFCD00956275
SCHEMBL377724
(2,6-dimethyl-4-pyridinyl)methanol
AB86594
AC-23055
DLDGHMPQNVTNRC-UHFFFAOYSA-N
W-206290
2,6-Dimethyl-4-(hydroxymethyl)pyridine
4-Pyridinemethanol, 2,6-dimethyl-
4-Hydroxymethyl-2,6-dimethylpyridine
TS-01776
4-(Hydroxymethyl)-2,6-dimethylpyridine
18088-01-2
AM85637
DTXSID50396925
(2,6-Dimethylpyridin-4-yl)methanol
2,6-Dimethyl-4-pyridylmethanol
4-Hydroxymethyl-2,6-lutidine

MDL Number

MFCD00956275

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2)?

(2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2) is a crystalline solid with a molecular weight of 147.15 g/mol. It has good solubility in common organic solvents like ethanol and acetone. It is moderately reactive, showing basic properties due to the methanol group. Typical physical properties include a melting point of 104-107°C and a density of 1.06 g/cm³.

How is (2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2) typically synthesized?

(2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2) can be synthesized via the reduction of 2,6-dimethyl-4-pyridone with methanol in the presence of a catalyst such as sodium methoxide. Common methods include the use of hydrogenation in the presence of palladium catalysts or direct reduction with sodium methoxide in a suitable solvent. The yield is generally between 70-80%, with good selectivity toward the methanol derivative.

What industries use (2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2)?

(2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2) finds applications in various industries. It is used in the pharmaceutical sector as an intermediate in the synthesis of drugs. It also plays a role in the production of polymers, where it serves as a functional monomer. Additionally, it is utilized in the development of sensors and semiconductors due to its chemical properties.

What precautions should be taken when handling (2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2)?

When handling (2,6-Dimethyl-4-pyridinyl)methanol (CAS: 18088-01-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.