Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate | CAS No. 180587-75-1

Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate

Basic Information

CAS Number

180587-75-1

Molecular Formula

C13H22N5O4P

Molecular Weight

343.32 g/mol

AD

Basic Physical Properties

Melting Point

107-109°C

CCOP(=O)(COC(C)Cn1cnc2c1ncnc2N)OCC

InChI

InChI=1S/C13H22N5O4P/c1-4-21-23(19,22-5-2)9-20-10(3)6-18-8-17-11-12(14)15-7-16-13(11)18/h7-8,10H,4-6,9H2,1-3H3,(H2,14,15,16)/t10-/m1/s1

InChIKey

GCOFRXOOFANVPB-SNVBAGLBSA-N

LogP

2.0372

Topological Polar Surface Area

114.38000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Synonyms & References

English

  • (R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
  • 9-[(2S)-2-(diethoxyphosphorylmethoxy)propyl]purin-6-amine
  • Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, diethyl ester
  • tenofovir diethyl ester
  • Diethyl Tenofovir
  • Tenofovir disoproxil Impurity V
  • (R)-9-[2-(Diethylphosphonomethoxy)propy] Adenine
  • (R)-diethyl (1-(6-aMino-9H-purin-9-yl)propan-2-yloxy)Methylphosphonate
  • [[(1R)-2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]phosphonic Acid Diethyl Ester
  • P-[[(1R)-2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]phosphonic Acid Diethyl Ester

MDL Number

MFCD07369331

FAQ

What is Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 180587-75-1)?

Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate is a chemical compound with the CAS number 180587-75-1. It is a complex organic molecule that includes phosphonate and amino purine derivatives. This compound is characterized by its stability and specific functional groups, making it useful in various applications.

What are the main uses of Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 180587-75-1)?

Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate is primarily used in pharmaceutical research and development, as it can serve as a precursor or intermediate in the synthesis of various drugs. It is also utilized in academic and industrial settings for its unique chemical properties.

Is Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 180587-75-1) safe?

Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate is generally considered safe when handled with appropriate precautions. However, it is important to follow safety guidelines, including the use of gloves and protective eyewear, to avoid skin contact and inhalation. Ensure proper ventilation and avoid exposure to heat or flames.

How should Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 180587-75-1) be stored?

Diethyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate should be stored in a cool, dry place away from direct sunlight and heat sources. Maintain a temperature below 25°C and store in a tightly sealed container to prevent degradation. Humidity should be kept low to avoid moisture absorption, which could affect its stability.

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