8-Aminoguanosine

Basic Information

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CAS Number

180288-69-1

Molecular Formula

C10H14N6O5

Molecular Weight

298.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C([C@@H]1[C@H]([C@H]([C@@H](O1)n2c3c(c(=O)[nH]c(n3)N)nc2N)O)O)O

InChI

InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1

InChIKey

FNXPTCITVCRFRK-UMMCILCDSA-N

LogP

-3.1044999999999994

Topological Polar Surface Area

185.52999999999997 Å²

Hydrogen Bond Donor/Acceptor

8 / 11

Synonyms & References

English

Trastuzumab
Herceptin
TrastuzuMab(Herceptin)
IMMunoglobulin G1,anti-(huMan p185neu receptor) (huMan-Mouse Monoclonal rhuMab HER2 g1-chain), disulfide with huMan-MouseMonoclonal rhuMab HER2 light chain, diMer
Anti HER2, Ig gamma-1 chain C region
Recombinant humanized anti-HER2 antibody
RhuMab HER2
Immunoglobulin G1,anti-(human p185neu receptor) (human-mouse monoclonal rhuMab HER2 g1-chain),...
Immunoglobulin G 1 (human-mouse monoclonal rhuMab HER2gamma1-chain antihuman p185(sup c-erbB2) receptor), disulfide with human-mouse monoclonal rhuMab HER2 light chain, dimer
Immunoglobulin G1, anti-(human p185neu receptor) (human-mouse monoclonal rhuMab HER2 gamma1-chain), disulfide with human-mouse monoclonal rhuMab HER2 light chain, dimer
Trastuzumab [USAN:INN]
UNII-P188ANX8CK
TRASTUZUMAB 95 % +
TRASTUZUMAB 98 % +

FAQ

What is 8-Aminoguanosine (CAS: 180288-69-1)?

8-Aminoguanosine is a modified form of guanosine, an important nucleoside that serves as a building block for RNA. It has a CAS number of 180288-69-1. This compound is characterized by its ability to form adducts with DNA and RNA, making it useful in research and pharmaceutical applications.

What are the main uses of 8-Aminoguanosine (CAS: 180288-69-1)?

8-Aminoguanosine is primarily used in research for studying DNA and RNA adduct formation, as a potential therapeutic agent for certain diseases, and in the development of chemotherapeutic drugs. It is also used in the pharmaceutical industry to investigate the effects of nucleoside modifications on biological systems.

Is 8-Aminoguanosine (CAS: 180288-69-1) safe?

8-Aminoguanosine is generally considered safe when used under proper laboratory conditions and handled with appropriate precautions. However, it is important to follow safety guidelines, wear protective gear, and ensure proper ventilation. Direct contact with skin or eyes should be avoided, and it should be stored in a secure, labeled container away from heat and light.

How should 8-Aminoguanosine (CAS: 180288-69-1) be stored?

8-Aminoguanosine should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. The storage temperature should be maintained between 2°C and 8°C to preserve its stability and effectiveness.