5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] | CAS No. 180160-48-9

5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine]

Basic Information

CAS Number

180160-48-9

Molecular Formula

C12H14ClNO

Molecular Weight

223.7 g/mol

AD

Basic Physical Properties

c1cc2c(cc1Cl)COC23CCNCC3

InChI

InChI=1S/C12H14ClNO/c13-10-1-2-11-9(7-10)8-15-12(11)3-5-14-6-4-12/h1-2,7,14H,3-6,8H2

InChIKey

ZUKZVXUSZUGBOH-UHFFFAOYSA-N

LogP

2.448900000000001

Topological Polar Surface Area

21.259999999999998 Ų

Hydrogen Bond Donor/Acceptor

1 / 2

Synonyms & References

English

  • 5-chloro-3H-spiro[isobenzofuran-1,4'-piperidine]
  • 6-chlorospiro[1H-2-benzofuran-3,4'-piperidine]
  • 5-chloro-3H-spiro[2-benzofuran-1,4'-piperidine]
  • 5-chlorospiro[isobenzofuran-1(3H),4'-piperidine]
  • AG-L-19722
  • AK-54422
  • ANW-52600
  • CTK4D7530
  • KB-245641
  • SureCN1275908

MDL Number

MFCD16876097

FAQ

What regulatory guidelines apply to 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9)?

5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9) falls under the provisions of the Chemicals Regulation Directive (CRD) in the EU, and is subject to the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation. Additionally, it is regulated by the U.S. Environmental Protection Agency (EPA) and the U.S. Food and Drug Administration (FDA) for safety and environmental protection purposes.

Are there alternatives to 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9) in synthesis?

Synthesis of 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] can explore alternatives such as 3H-spiro[2-benzofuran-1,4'-piperidine] or related analogs. Common alternative reagents include chloroacetic acid, chloroform, and other halogenated compounds. These can serve as effective substitutes in the synthesis process.

What is the market or research trend for 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9)?

The market for 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9) is driven by its applications in pharmaceuticals and research. Recent trends include its use as an intermediate in the synthesis of new drugs. Research is focusing on its potential as a therapeutic agent for various diseases, including neurological disorders and inflammatory conditions.

How should waste containing 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9) be handled?

Waste containing 5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] (CAS: 180160-48-9) should be collected in sealed containers and disposed of through professional waste disposal services. Incineration is a common method for disposal, and proper environmental precautions must be taken to prevent contamination. Compliance with local and national regulations is essential for safe disposal.

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