Ambrisentan Impurity 10

Basic Information

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CAS Number

177036-78-1

Molecular Formula

C17H18O4

Molecular Weight

286.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

440.7±40.0°C at 760 mmHg

SMILES

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COC(=O)C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OC)O

InChI

InChI=1S/C17H18O4/c1-20-16(19)15(18)17(21-2,13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15,18H,1-2H3/t15-/m1/s1

InChIKey

BEPLSLADXOJCBY-OAHLLOKOSA-N

LogP

2.1105

Topological Polar Surface Area

55.760000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

312

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

Methyl (2S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoate
(S)- 2-HYDROXY-3-METHOXY-3,3-DIPHENYLPROPANOIC ACID METHYL ESTER
(S)-2-hydroxy methyl 3-methoxy-3,3-diphenylpropionate
(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
(S)-Methyl 2-hydroxy-3-Methoxy-3,3-diphenylpropanoate
(S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid methyl este
AS-73060
FD7218
Methyl (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionate
AKOS015999150
(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid methyl ester
SCHEMBL2354447
(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid Methyl Ester; Ambrisentan Hydroxyester Impurity;
AC-26424
(S)-2-HYDROXY-3-METHOXY-3,3-DIPHENYLPROPIONIC ACID METHYL ESTER
Benzenepropanoic acid, alpha-hydroxy-beta-methoxy-beta-phenyl-, methyl ester, (alphaS)-
AMY14980
BEPLSLADXOJCBY-OAHLLOKOSA-N
DTXSID50442875
AC-26423
177036-78-1
A881481
Methyl(2S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoate
(S)-Alpha-Hydroxy-Beta-methoxy-Beta-phenyl-benzenepropanoic Acid Methyl Ester
MFCD11865341
CS-0061795
methyl (S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoate

MDL Number

MFCD11865341

Customs Code

2918990090

FAQ

What is Ambrisentan Impurity 10 (CAS: 177036-78-1)?

Ambrisentan Impurity 10 (CAS: 177036-78-1) is a byproduct of the synthesis of ambrisentan, a pulmonary arterial hypertension treatment. It is not used clinically but is an important impurity to monitor in the quality control of ambrisentan.

What are the main uses of Ambrisentan Impurity 10 (CAS: 177036-78-1)?

Ambrisentan Impurity 10 (CAS: 177036-78-1) has no direct therapeutic uses. Its main use is in the quality assurance of ambrisentan, ensuring the purity and consistency of the drug.

Is Ambrisentan Impurity 10 (CAS: 177036-78-1) safe?

Ambrisentan Impurity 10 (CAS: 177036-78-1) is generally safe when handled with proper precautions. It is important to follow safety guidelines to avoid inhalation, ingestion, or skin contact.

How should Ambrisentan Impurity 10 (CAS: 177036-78-1) be stored?

Ambrisentan Impurity 10 (CAS: 177036-78-1) should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation.