4,4'-Methylenedicyclohexanamine | CAS No. 1761-71-3

Q: What are the physical and chemical properties of 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is a colorless to white crystalline powder. Its molecular weight is approximately 238.42 g/mol. It has limited water solubility but is more soluble in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but reacts with strong acids and bases. It is commonly used in the synthesis of pharmaceuticals and polymers.

Q: How is 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) typically synthesized?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is typically synthesized by the cycloaddition reaction of 1,4-cyclohexadiene with methylene dichloride in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction provides a high yield and good selectivity for the desired product.

Q: What industries use 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is primarily used in the pharmaceutical and polymer industries. It is a key intermediate in the synthesis of various drugs and also serves as a monomer for the production of specialty polymers. Additionally, it finds applications in the manufacturing of sensors and semiconductors.

Q: What precautions should be taken when handling 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

When handling 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Operations should be conducted in a well-ventilated area or a fume hood. Spills should be carefully cleaned up, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.

4,4'-Methylenedicyclohexanamine

Basic Information

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CAS Number

1761-71-3

Molecular Formula

C13H26N2

Molecular Weight

210.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

60-65 ºC

Boiling Point

126°C/0.3mmHg

Flash Point

>230 °F

Refractive Index

1.5032 (estimate)

Vapor Pressure

<0.1 mm Hg ( 38 °C)

SMILES

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NC1CCC(CC2CCC(N)CC2)CC1

InChI

InChI=1S/C13H26N2/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h10-13H,1-9,14-15H2

InChIKey

DZIHTWJGPDVSGE-UHFFFAOYSA-N

LogP

2.4115

Topological Polar Surface Area

52.04 Å²

Hydrogen Bond Donor/Acceptor

4 / 2

Complexity

157

Safety Information

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Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H330 Fatal if inhaled
Acute toxicity, inhalation

H371 May cause damage to organs
Specific target organ toxicity, single exposure

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 8 Class 8

Synonyms & References

English

4,4'-Methylenedicyclohexanamine
4,4-Diaminodicyclohexylmethane
4,4-Methylenebis(cyclohexylamine)
Bis(4-aminocyclohexyl)methane
4,4'-diaminodicyclohexylmethane
4,4'-Methylenebis(cyclohexylamine) (mixture of isomers)
4-((4-aminocyclohexyl)methyl)cyclohexanamine
4,4'-methylene bis(cyclohexylamine)
4,4'-Methylenebis(aminocyclohexane)
bis(para-amino-cyclohexyl)methane
di(4-aminocyclohexyl)-methane
DICYKAN
HLR 4219
hlr4448
PACM20
p-aminodicyclohexylmethane
TRANS,TRANS-4,4'-METHYLENEBIS(CYCLOHEXYLAMINE)
wandaminhm
Wondamine HM
Bis(4-aminocyclohexyl)methane (mixture of isomers)
4,4'-Diaminodicyclohexylmethane (mixture of isomers)
4,4'-Methylenebis(aminocyclohexane) (mixture of isomers)
Amicure PACM
4,4'-Diaminodicyclohexyl methane
4,4'-Methylenebis(cyclohexylamine)
hlr4219
HLR 4448
Wandamin hm

MDL Number

MFCD00001496

Customs Code

2921300090

FAQ

What are the physical and chemical properties of 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is a colorless to white crystalline powder. Its molecular weight is approximately 238.42 g/mol. It has limited water solubility but is more soluble in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but reacts with strong acids and bases. It is commonly used in the synthesis of pharmaceuticals and polymers.

How is 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) typically synthesized?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is typically synthesized by the cycloaddition reaction of 1,4-cyclohexadiene with methylene dichloride in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction provides a high yield and good selectivity for the desired product.

What industries use 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3) is primarily used in the pharmaceutical and polymer industries. It is a key intermediate in the synthesis of various drugs and also serves as a monomer for the production of specialty polymers. Additionally, it finds applications in the manufacturing of sensors and semiconductors.

What precautions should be taken when handling 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3)?

When handling 4,4'-Methylenedicyclohexanamine (CAS: 1761-71-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Operations should be conducted in a well-ventilated area or a fume hood. Spills should be carefully cleaned up, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.