2-[(2-Hydroxybenzylidene)amino]phenol

Basic Information

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CAS Number

1761-56-4

Molecular Formula

C13H11NO2

Molecular Weight

213.24 g/mol

Chemical Classification

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

185.0 to 189.0 deg-C

SMILES

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OC1=CC=CC=C1/N=C/C2=CC=CC=C2O

InChI

InChI=1S/C13H11NO2/c15-12-7-3-1-5-10(12)9-14-11-6-2-4-8-13(11)16/h1-9,15-16H

InChIKey

CHBGIQHEGBKNGA-UHFFFAOYSA-N

LogP

2.848400000000001

Topological Polar Surface Area

52.82000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

242

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

o-Salicylideneaminophenol
2-SALICYLIDENEAMINOPHENOL
2-([(2-hydroxyphenyl)imino]methyl) phenol
2-(2-HYDROXYBENZYLIDENEAMINO)PHENOL
2-(salicylidenamino)phenol
2-[(o-hydroxylphenylimino)methyl]phenol
Manganon
o-(Salicylidenimino)phenol
Salicylal-2-aminophenol
Salicylal-o-aminophenol
SALICYLIDENE-O-AMINOPHENOL
SAPH【Dotite】
TIMTEC-BB SBB008244
N-Salicylidene-o-aminophenol
o-(Salicylideneamino)phenol
2-Hydroxyanilinosalicylidene
2-((2-Hydroxybenzylidene)amino)phenol
2-(Salicylideneamino)phenol
2-Hydroxy-N-salicylideneaniline
Phenol, o-(salicylideneamino)-
o-Hydroxy-N-salicylidene aniline
N-(2-Hydroxyphenyl)salicylaldimine
Phenol, 2-[[(2-hydroxyphenyl)imino]methyl]-
O-SALICYLIDENEAMINOPHENOL

MDL Number

MFCD00020011

Customs Code

2925290090

FAQ

What are the physical and chemical properties of 2-[(2-Hydroxybenzylidene)amino]phenol (CAS: 1761-56-4)?

2-[(2-Hydroxybenzylidene)amino]phenol is a white to off-white crystalline solid with a molecular weight of approximately 222.21 g/mol. It has a moderate solubility in water (2.5 g/L at 25°C) and poor solubility in common organic solvents. The compound is moderately reactive towards bases and reducing agents. It is stable under normal storage conditions but should be protected from strong acids and oxidizing agents.

How is 2-[(2-Hydroxybenzylidene)amino]phenol (CAS: 1761-56-4) typically synthesized?

2-[(2-Hydroxybenzylidene)amino]phenol can be synthesized via a condensation reaction between 2-hydroxybenzaldehyde and phenylhydrazine. This process is catalyzed by a strong base like sodium hydroxide and typically yields the product in good to high yield. The reaction is performed in a solvent such as ethanol, and the intermediate is purified by recrystallization.

What industries use 2-[(2-Hydroxybenzylidene)amino]phenol (CAS: 1761-56-4)?

2-[(2-Hydroxybenzylidene)amino]phenol is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also has applications in the polymer industry for preparing functionalized polymers, and in the development of sensors and semiconductors due to its photoreactivity.

What precautions should be taken when handling 2-[(2-Hydroxybenzylidene)amino]phenol (CAS: 1761-56-4)?

When handling 2-[(2-Hydroxybenzylidene)amino]phenol, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. In case of a spill, the area should be decontaminated using appropriate cleaning agents, and the material safety data sheet (MSDS) should be consulted for specific spill procedures. Storage should be in a cool, dry place away from strong acids and oxidizing agents.