[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine

Basic Information

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CAS Number

175277-74-4

Molecular Formula

C7H6ClF3N2

Molecular Weight

210.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

226 °C

Boiling Point

212.0±35.0 ºC (760 Torr),

Flash Point

82.0±25.9 ºC,

Refractive Index

1.488

SMILES

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C1=C(C=NC(=C1Cl)CN)C(F)(F)F

InChI

InChI=1S/C7H6ClF3N2/c8-5-1-4(7(9,10)11)3-13-6(5)2-12/h1,3H,2,12H2

InChIKey

JVQYWHGODHSTAM-UHFFFAOYSA-N

LogP

2.2125000000000004

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

174

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-PYRIDINEMETHANAMINE, 3-CHLORO-5-(TRIFLUOROMETHYL)-
2-AMINOMETHYL-3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE
YSSJ00065
MFCD00178759
CS-0099288
SCHEMBL635541
AKOS016001120
2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)pyridine
1-[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]METHANAMINE
EN300-6478021
3-chloro-5-trifluoromethylpyridin-2-ylmethylamine
2-aminomethyl-3-chloro-5-trifluoromethylpyridine
(3-chloro-5-(trifluoromethyl)pyridin-2-yl)methanamine
AB04403
C7H7Cl2F3N2
[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine
[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine
JVQYWHGODHSTAM-UHFFFAOYSA-O
175277-74-4
2-aminomethyl-3-chloro-5-(trifluoromethyl)pyridine, AldrichCPR
(3-chloro-5-trifluoromethyl-2-pyridyl)methylamine
2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)-
BUTTPARK 145\04-45
[3-Chloro-5-(trifluoromethyl)-2-pyridyl]methylamine hydrochloride
(3-chloro-5-(trifluoromethyl)pyridin-2-yl)methanamine hydrochloride
[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine hydrochloride
3-chloro-2-aminomethyl-5-(trifluoromethyl) pyridine
[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-methanamine hydrochloride
2-(AMINOMETHYL)-3-CHLORO-5-(TRIFLUOROMETHYL)-PYRIDINE HYDROCHLORIDE
2-Aminomethyl-3-chloro-5-(trifluoromethyl)pyridine
(3-chloro-5-trifluoromethyl-pyridin-2-yl)methylamine

MDL Number

MFCD00178759

Customs Code

2933399090

FAQ

What is [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine (CAS: 175277-74-4)?

[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine is a chemical compound with the CAS number 175277-74-4. It is a white to off-white powder at room temperature and is characterized by its high stability and low volatility. This compound contains a chlorine atom, a trifluoromethyl group, and a pyridine ring, making it a versatile intermediate in organic synthesis.

What are the main uses of [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine (CAS: 175277-74-4)?

[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine is primarily used as an intermediate in the pharmaceutical industry. It is employed in the synthesis of various drugs and also serves in the production of other chemical compounds. Its stability and specific functional groups make it valuable in organic synthesis for creating complex molecules.

Is [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine (CAS: 175277-74-4) safe?

[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine is generally considered safe when handled with appropriate precautions. However, it is important to note that it can be irritating to the eyes and skin. It is essential to wear protective gloves, goggles, and appropriate clothing when handling this compound. Avoid contact with eyes, skin, and inhalation of dust. Ensure proper ventilation in the work area.

How should [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine (CAS: 175277-74-4) be stored?

[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methanamine should be stored in a cool, dry place, away from direct sunlight and heat sources. It is recommended to keep it in a tightly sealed container to prevent degradation. Store it in a well-ventilated area to avoid the accumulation of potentially flammable gases. Do not store it near incompatible materials such as strong acids or oxidizers. Follow the manufacturer's guidelines for specific storage instructions.