3-(4-Chlorophenyl)-1-methoxy-1-methylurea

Basic Information

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CAS Number

1746-81-2

Molecular Formula

C9H11ClN2O2

Molecular Weight

214.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

81.5 ºC

Refractive Index

1.5790 (estimate)

SMILES

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CN(C(=O)NC1=CC=C(C=C1)Cl)OC

InChI

InChI=1S/C9H11ClN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)

InChIKey

LKJPSUCKSLORMF-UHFFFAOYSA-N

LogP

2.3651

Topological Polar Surface Area

41.57000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

193

Safety Information

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GHS Hazard Pictograms

H302

H373

H410

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

A924734
MLS000058831
SMR000069097
Arezine
Arresin
Monolinuron 10 microg/mL in Acetonitrile
DTXSID0037576
N'-(4-Chlorophenyl)-N-methoxy-N-methylurea
CHEMBL1320234
s10380
Monolinuron 100 microg/mL in Acetonitrile
LKJPSUCKSLORMF-UHFFFAOYSA-N
DS-16467
J-011027
CHEBI:81965
Monolinuron [BSI:ISO]
1746-81-2
BRN 2212523
Urea, N'-(4-chlorophenyl)-N-methoxy-N-methyl-
SCHEMBL65568
Urea, 3-(p-chlorophenyl)-1-methoxy-1-methyl-
Tox21_301360
Monolinuron, PESTANAL(R), analytical standard
3-(4-Chlorphenyl)-1-methoxy-1-methylharnstoff
DTXCID8017576
Q6901670
EINECS 217-129-5
MONOLINURON [ISO]
Caswell No. 207D
N-(4-Chlorophenyl)-N'-methoxy-N-methylurea
UNII-6KJJ4XAD6M

MDL Number

MFCD00055264

FAQ

What are the physical and chemical properties of 3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2)?

3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2) is a crystalline solid with a molecular weight of approximately 229.65 g/mol. It has a solubility of about 1.3 g/L in water. The compound is relatively stable but may react with strong acids or bases. It is insoluble in common organic solvents like ethanol and acetone.

How is 3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2) typically synthesized?

3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2) is typically synthesized via a multistep process involving the reaction of 4-chloroaniline with methyl isocyanate in the presence of a base. The method provides good yield and selectivity, although specific conditions may vary.

What industries use 3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2)?

3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2) is used in the pharmaceutical industry for the synthesis of certain drugs. It also has applications in the polymer industry for the modification of polymer properties and in the sensor industry due to its reactivity.

What precautions should be taken when handling 3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2)?

When handling 3-(4-Chlorophenyl)-1-methoxy-1-methylurea (CAS: 1746-81-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle in a well-ventilated area or fume hood to avoid inhalation. Spills should be handled carefully, and the Material Safety Data Sheet (MSDS/SDS) should be consulted for specific spill procedures.