2-Bromo-5-chlorobenzaldehyde

Basic Information

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CAS Number

174265-12-4

Molecular Formula

C7H4BrClO

Molecular Weight

219.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

64.0 to 68.0 deg-C

Boiling Point

258 ºC

Flash Point

110 ºC

Refractive Index

1.623

SMILES

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C1=CC(=C(C=C1Cl)C=O)Br

InChI

InChI=1S/C7H4BrClO/c8-7-2-1-6(9)3-5(7)4-10/h1-4H

InChIKey

IIISHLMCTDMUHH-UHFFFAOYSA-N

LogP

2.915000000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

129

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

CL8256
J-508270
2-Bromo-5-chlorobenzaldehyde
B2955
SY021852
IIISHLMCTDMUHH-UHFFFAOYSA-
PS-7884
Z871833038
2-Bromo-5-chlorobenzaldehyde, AldrichCPR
A3852
5-CHLORO-2-BROMOBENZALDEHYDE
Benzaldehyde, 2-bromo-5-chloro-
DTXSID40572312
FT-0602295
AC-26756
EN300-57064
AKOS005257149
InChI=1/C7H4BrClO/c8-7-2-1-6(9)3-5(7)4-10/h1-4H
MFCD00462870
BCP05871
CS-W007422
SCHEMBL380473
AM20060802
IIISHLMCTDMUHH-UHFFFAOYSA-N
W-206063
174265-12-4
5-Chloro-2-bromobenzaldehyde
Benzaldehyde,2-bromo-5-chloro
IIISHLMCTDMUHH-UHFFFAOYSA
2-Bromo-5-chlorobenzalde
PubChem19849

MDL Number

MFCD00462870

Customs Code

2913000090

FAQ

What are the physical and chemical properties of 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4)?

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) is a crystalline solid with a molecular weight of approximately 227.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, showing both electrophilic aromatic substitution and nucleophilic addition reactivity. It is commonly used in organic synthesis as a functionalized benzaldehyde derivative.

How is 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) typically synthesized?

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) can be synthesized via the bromination and chlorination of benzaldehyde followed by coupling reactions. Common methods include the sequential use of brominating agents like N-bromosuccinimide (NBS) and chlorinating agents such as thionyl chloride (SOCl2). This process requires careful control of reaction conditions to achieve high selectivity and yield.

What industries use 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4)?

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) is used in various industries, including pharmaceuticals for the synthesis of intermediates, polymers for functionalizing polymer chains, and sensors for detecting specific chemical species. It also finds application in semiconductor manufacturing for modifying surface properties.

What precautions should be taken when handling 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4)?

When handling 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbents, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.