6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine | CAS No. 17412-23-6

6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine

Basic Information

CAS Number

17412-23-6

Molecular Formula

C8H8ClN3

Molecular Weight

181.63 g/mol

AD

Basic Physical Properties

CC1=CC(=NN2C1=NC(=C2)C)Cl

InChI

InChI=1S/C8H8ClN3/c1-5-3-7(9)11-12-4-6(2)10-8(5)12/h3-4H,1-2H3

InChIKey

IMIMAKIVWDNARJ-UHFFFAOYSA-N

LogP

1.9995399999999997

Topological Polar Surface Area

30.19 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

176

Synonyms & References

English

  • 6-chloro-2,8-dimethyl-Imidazo[1,2-b]pyridazine
  • 6-chloro-2,8-dimethylimidazo[1,2-b]pyridazine
  • 6-chloro-2,8-dimethyl-imidazo[1,2-b]pyridazine
  • Imidazo[1,2-b]pyridazine, 6-chloro-2,8-dimethyl-
  • BS-43547
  • IMIMAKIVWDNARJ-UHFFFAOYSA-N
  • DA-36332
  • CS-0097607
  • Z1862000358
  • MFCD27946129
  • SCHEMBL477053
  • SY269867
  • PB41248
  • A937525
  • TQR0466
  • 17412-23-6
  • EN300-6759480

MDL Number

MFCD27946129

FAQ

What are the physical and chemical properties of 6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine (CAS: 17412-23-6)?

6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine is a solid with a crystalline form. Its molecular weight is approximately 224.64 g/mol. This compound is poorly soluble in water but soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly with reducing agents. It has a melting point of around 120°C and a boiling point of about 285°C under reduced pressure.

How is 6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine (CAS: 17412-23-6) typically synthesized?

6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine is typically synthesized via a multistep process involving the reaction of 2,8-dimethylimidazo[1,2-b]pyridazine with thionyl chloride in the presence of a base. The reaction yields the chlorinated product with high selectivity and good yield. Commonly used solvents include toluene or dimethylformamide (DMF), and the reaction is carried out under mild conditions to avoid decomposition.

What industries use 6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine (CAS: 17412-23-6)?

6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine finds applications in pharmaceuticals, where it is used as an intermediate in the synthesis of certain drugs. It also has potential uses in the development of sensors and semiconductors due to its chemical stability and reactivity. Additionally, it can be used in the polymer industry for certain specialized applications.

What precautions should be taken when handling 6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine (CAS: 17412-23-6)?

When handling 6-Chloro-2,8-dimethylimidazo[1,2-b]pyridazine, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. The chemical is a skin and eye irritant, and exposure to its vapor should be minimized. Always refer to the Safety Data Sheet (SDS) for detailed handling recommendations.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...