alpha-Methyl-D-phenylalanine

Basic Information

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CAS Number

17350-84-4

Molecular Formula

C10H13NO2

Molecular Weight

179.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

312.8±30.0 °C at 760 mmHg

Density

1.1660

Flash Point

143.0±24.6 °C

SMILES

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CC(CC1=CC=CC=C1)(C(=O)O)N

InChI

InChI=1S/C10H13NO2/c1-10(11,9(12)13)7-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)/t10-/m1/s1

InChIKey

HYOWVAAEQCNGLE-SNVBAGLBSA-N

LogP

1.0311000000000001

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

187

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Sensitiveness

Prone to moisture absorption

Synonyms & References

English

D-ALPHA-METHYL PHENYLALANINE
MFCD00153491
(R)-alpha-methyl phenylalanine
DTXSID001313216
SCHEMBL202327
A811521
BDBM50463193
alpha-Methyl-D-phenylalanine, >=98.0% (HPLC)
HYOWVAAEQCNGLE-SNVBAGLBSA-N
A-Methyl-D-phenylalanine
(r)-alpha-methylphenyl-alanine
A inverted exclamation mark-Benzyl-D-Ala
F10695
AB04114
alpha-methyl-D-Phe
D-Phenylalanine, alpha-methyl-
DS-16370
EN300-755615
CHEMBL4250045
AKOS016843198
17350-84-4
(R)-alpha-Methylphenylalanine
ALPHA-BENZYL-D-ALA
ALPHA-METHYL-D-PHENYLALANINE
AC-4461
a-methyl-d-phenylalanine
J-010914
(R)-2-Amino-2-methyl-3-phenylpropanoic acid
(2R)-2-amino-2-methyl-3-phenylpropanoic acid
alpha -Methyl-D-phenylalanine

MDL Number

MFCD00153491

Customs Code

2922499990

FAQ

What are the physical and chemical properties of alpha-Methyl-D-phenylalanine (CAS: 17350-84-4)?

Alpha-Methyl-D-phenylalanine (CAS: 17350-84-4) is a crystalline solid with a molecular weight of approximately 202.24 g/mol. It is slightly soluble in water but soluble in organic solvents like methanol and ethanol. Chemically, it is stable under normal conditions but can undergo hydrolysis in the presence of moisture. It is a chiral compound with a melting point around 226-228°C.

How is alpha-Methyl-D-phenylalanine (CAS: 17350-84-4) typically synthesized?

Alpha-Methyl-D-phenylalanine (CAS: 17350-84-4) is typically synthesized via the condensation of D-phenylalanine with alpha-methyl-1-naphthylamine using a condensing agent like dicyclohexylcarbodiimide (DCC) and 4-(dimethylamino)pyridine (DMAP) as a catalyst. The reaction is carried out in an organic solvent such as dichloromethane, with a high yield of up to 90%.

What industries use alpha-Methyl-D-phenylalanine (CAS: 17350-84-4)?

Alpha-Methyl-D-phenylalanine (CAS: 17350-84-4) is used in the pharmaceutical industry for the synthesis of certain peptides and in the food industry as a flavor enhancer. It is also utilized in the production of polymers and as a precursor in the development of sensors and semiconductors.

What precautions should be taken when handling alpha-Methyl-D-phenylalanine (CAS: 17350-84-4)?

When handling alpha-Methyl-D-phenylalanine (CAS: 17350-84-4), it is important to use personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. The substance should be handled in a fume hood to avoid inhalation. Spills should be immediately cleaned up with water and soap, and the area should be thoroughly ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information.