(5S)-5-(Hydroxymethyl)-2-pyrrolidinone

Basic Information

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CAS Number

17342-08-4

Molecular Formula

C5H9NO2

Molecular Weight

115.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

82.0 to 87.0 deg-C

Boiling Point

346°C at 760 mmHg

Water Solubility

Soluble in water.

Flash Point

147-149℃/0.06m

Refractive Index

31 ° (C=5, EtOH)

Specific Rotation

30 º (c=2, EtOH)

SMILES

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C1CC(=O)NC1CO

InChI

InChI=1S/C5H9NO2/c7-3-4-1-2-5(8)6-4/h4,7H,1-3H2,(H,6,8)/t4-/m0/s1

InChIKey

HOBJEFOCIRXQKH-BYPYZUCNSA-N

LogP

-0.7427000000000004

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

103

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(s)-pyroglutaminol
EN300-27221
17342-08-4
(S)-5-(Hydroxymethyl)-2-pyrrolidinone
Q-102735
AS-11453
(5S)-5-(hydroxymethyl)pyrrolidin-2-one
AKOS016015259
Z235344345
DTXSID80349207
HOBJEFOCIRXQKH-BYPYZUCNSA-N
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-
(S)-(+)-5-(hydroxymethyl)pyrrolidin-2-one
(s)-(+)-5-hydroxymethyl-2-pyrrolidinone
A3834
Q-200037
(S)-5-(hydroxymethyl)pyrrolidin-2-one
CS-B0366
L-Pyroglutaminol
(5S)-5-(hydroxymethyl)tetrahydro-1H-2-pyrrolone
5-oxoprolinol
(S)-5-hydroxymethylpyrrolidin-2-one
SCHEMBL210597
AM20090035
(5S)-5-(hydroxymethyl)-2-pyrrolidinone
(S)-5(Hydroxymethyl)-2-pyrrolidinone
(S)-5-(Hydroxymethyl)-2-pyrrolidinone, 97%
CHEMBL4559630
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
(S)-5-hydroxymethyl-pyrrolidin-2-one
H0867

MDL Number

MFCD00077792

Customs Code

2933790090

FAQ

What regulatory guidelines apply to (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4)?

The compound (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) is subject to various regulatory guidelines. It falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), and may require classification as a chemical reagent. In the European Union, it is regulated by REACH, which requires manufacturers and importers to register substances and provide safety data sheets. Additionally, the FDA and EPA may have specific requirements for this compound in pharmaceutical and environmental contexts.

Are there alternatives to (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) in synthesis?

There are several alternatives to (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) in synthesis, including other pyrrolidinones and related cyclic amines. Common substitutes include (5R)-5-(Hydroxymethyl)-2-pyrrolidinone and 2-pyrrolidone. These alternatives can serve similar functions in various chemical processes, offering flexibility in the synthesis of organic compounds.

What is the market or research trend for (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4)?

The market for (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) is growing due to its applications in pharmaceuticals, cosmetics, and as a solubility enhancer. Research trends are focused on its use in drug delivery systems and as a protective agent in organic synthesis. There is also increasing interest in its environmental impact and biodegradability, which are key factors in its wider adoption.

How should waste containing (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) be handled?

Waste containing (5S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4) should be collected in appropriate containers and stored separately from other materials. For disposal, it is recommended to consult local regulations, but generally, it should be incinerated or processed by a professional waste disposal service. Environmental precautions include ensuring no spills and proper ventilation during handling to minimize exposure and environmental contamination.