Atenolol EP Impurity A

Basic Information

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CAS Number

17194-82-0

Molecular Formula

C8H9NO2

Molecular Weight

151.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

175.0 to 179.0 deg-C

Boiling Point

403.9 ℃ at 760 mmHg

Flash Point

198.1±24.0 °C

Refractive Index

1.5810 (estimate)

Vapor Pressure

0.0±1.0 mmHg at 25°C

SMILES

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C1=CC(=CC=C1CC(=O)N)O

InChI

InChI=1S/C8H9NO2/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4,10H,5H2,(H2,9,11)

InChIKey

YBPAYPRLUDCSEY-UHFFFAOYSA-N

LogP

0.4199999999999999

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

139

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

InChI=1/C8H9NO2/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4,10H,5H2,(H2,9,11)
17194-82-0
2-(4-Hydroxyphenyl)-ethylamide
4-Hydroxybenzeneacetamide
p-(Carbamoylmethyl)phenol
Acetamide, 2-(p-hydroxyphenyl)-
BDBM50339587
H0853
s12297
(p-Hydroxyphenyl)acetamide
p-Hydroxyphenylacetamide
Benzeneacetamide, 4-hydroxy-
AKOS005716492
A811367
CHEMBL447310
FT-0618730
W-107869
P-HYDROXY BENZYLAMIDE
4-hydroxy phenylacetamide
3-10-00-00434 (Beilstein Handbook Reference)
4-Hydroxyphenylacetamide
(4-Hydroxyphenyl)acetamide
alpha-(p-Hydroxyphenyl)acetamide
0HY0N4ITN4
CHEBI:194828
YBPAYPRLUDCSEY-UHFFFAOYSA-
SCHEMBL661973
AC-6787
MFCD00017145
4-Hydroxyphenylacetamide, 99%
NSC-187193

MDL Number

MFCD00017145

Customs Code

2924299090

FAQ

What is Atenolol EP Impurity A (CAS: 17194-82-0)?

Atenolol EP Impurity A (CAS: 17194-82-0) is a chemical compound identified as a byproduct of Atenolol synthesis. It has the molecular formula C21H27NO5 and appears as a white to off-white crystalline solid. This impurity is commonly analyzed in pharmaceutical quality control to ensure drug purity and safety.

What are the main uses of Atenolol EP Impurity A (CAS: 17194-82-0)?

Atenolol EP Impurity A (CAS: 17194-82-0) is primarily used in pharmaceutical research and manufacturing for impurity profiling and quality assurance. It helps in detecting trace contaminants during the production of Atenolol, a beta-blocker medication. Additionally, it serves as a reference standard in analytical chemistry for method validation.

Is Atenolol EP Impurity A (CAS: 17194-82-0) safe?

Atenolol EP Impurity A (CAS: 17194-82-0) is generally considered safe in controlled laboratory conditions when handled properly. However, as with all chemicals, it requires adherence to safety protocols, such as wearing gloves and ensuring adequate ventilation. Its toxicity is low, but safety standards emphasize avoiding ingestion and skin contact to prevent potential adverse effects.

How should Atenolol EP Impurity A (CAS: 17194-82-0) be stored?

Atenolol EP Impurity A (CAS: 17194-82-0) should be stored in a cool, dry place, away from direct light, in a sealed container to maintain stability. It is typically stable under these conditions but should be protected from moisture and high temperatures to prevent degradation. Proper storage ensures its integrity for analytical use.