(1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol

Basic Information

View in Editor

CAS Number

1707-77-3

Molecular Formula

C12H22O6

Molecular Weight

262.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

117.0 to 123.0 deg-C

Boiling Point

382°C at 760 mmHg

Density

1.1750

Flash Point

184.8 °C

Solubility

methanol: 100 mg/mL, clear, colorless

Refractive Index

6.5 ° (C=8, CHCl3)

Specific Rotation

6 º (c=5, Chloroform)

SMILES

View in Editor

CC1(OCC(O1)C(C(C2COC(O2)(C)C)O)O)C

InChI

InChI=1S/C12H22O6/c1-11(2)15-5-7(17-11)9(13)10(14)8-6-16-12(3,4)18-8/h7-10,13-14H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1

InChIKey

ODYBCPSCYHAGHA-ZYUZMQFOSA-N

LogP

0.011199999999999433

Topological Polar Surface Area

77.38000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

273

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Sensitive to moisture

Synonyms & References

English

MFCD00003211
SCHEMBL768294
Diacetone-D-mannitol
HY-I0703
NSC 89874
1707-77-3
NSC 47987
D2024
F10687
1,2:5,6-Di-O-isopropylidene-D-mannitol
NSC 67545
D-Mannitol 1,2:5,6-bis-acetonide
D-Mannitol diacetonide
AKOS015919884
(1S,2S)-1,2-BIS((R)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)ETHANE-1,2-DIOL
Amido Black Staining Solution 2X,Amido Black 10B, Naphthol Blue Black solution
(1S,2S)-1,2-bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol
AKOS015924771
AC-8562
ODYBCPSCYHAGHA-ZYUZMQFOSA-N
6-Bromo-3-fluoro-2-methoxyphenylboronicacid
J-650223
AS-16068
1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
D-Mannitol,1,2:5,6-bis-O-(1-methylethylidene)-
1,2,5,6-di-O-Isopropylidene-D-mannitol
D-Mannitol1,2:5,6-bis-acetonide
1,2:5,6-Di-O-isopropylidene-D-mannitol, 98%
EINECS 216-954-8
1,2,5,6-diacetone D-mannitol
DTXSID201284699

MDL Number

MFCD00003211

Customs Code

2932999099

FAQ

What is (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol (CAS: 1707-77-3)?

The compound (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol, with CAS number 1707-77-3, is a chiral diol that contains two 2,2-dimethyl-1,3-dioxolan-4-yl groups attached to an ethane backbone. It is known for its stability and is commonly used in organic synthesis as a building block for more complex molecules. Its stereochemistry plays a key role in determining its chemical behavior and reactivity.

What are the main uses of (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol (CAS: 1707-77-3)?

This compound is primarily used in pharmaceutical research for the development of chiral drugs, as its stereochemistry can influence drug efficacy and safety. It also finds applications in the synthesis of polymeric materials and as a protective group in organic chemistry. Additionally, it is utilized in the creation of certain specialty chemicals and in chemical research for studying stereochemical effects.

Is (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol (CAS: 1707-77-3) safe?

The safety of (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol (CAS 1707-77-3) depends on its application. It is generally considered safe in controlled laboratory settings when handled properly. However, standard safety precautions such as using personal protective equipment and ensuring proper ventilation should be followed. As with all chemicals, it should be used in accordance with established safety guidelines and regulations.

How should (1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,2-ethanediol (CAS: 1707-77-3) be stored?

This compound should be stored in a cool, dry, and dark place, preferably at temperatures below 25°C. It is important to maintain low humidity levels to prevent degradation. It should be kept in a sealed container made of a material compatible with its chemical properties, such as glass or high-density polyethylene. Avoid exposure to light and ensure it is stored away from incompatible substances to maintain stability and safety.