N-Carbamoyl-4-methylbenzenesulfonamide

Basic Information

View in Editor

CAS Number

1694-06-0

Molecular Formula

C8H10N2O3S

Molecular Weight

214.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

196-198 ºC

Refractive Index

1.5690 (estimate)

SMILES

View in Editor

CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N

InChI

InChI=1S/C8H10N2O3S/c1-6-2-4-7(5-3-6)14(12,13)10-8(9)11/h2-5H,1H3,(H3,9,10,11)

InChIKey

RUTYWCZSEBLPAK-UHFFFAOYSA-N

LogP

0.3520199999999998

Topological Polar Surface Area

89.25999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

299

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Oprea1_528210
P-TOLYLSULFONYLUREA
4,7,7-trimethylnorbornan-2-ol;N-Carbamoyl-4-methylbenzenesulfonamide
FT-0633778
NS00025557
MFCD00196522
FS-3527
Q9W3K7K5XB
4-Toluenesulfonylurea
DS-1957
Benzenesulfonamide, N-(aminocarbonyl)-4-methyl-
J-010537
p-Toluolsulfonyl-harnstoff
(4-methylphenyl)sulfonylurea
TOLUENESULFONYLUREA [EP IMPURITY]
AKOS003624899
N-(Aminocarbonyl)-4-methylbenzenesulphonamide
p-Toluenesulfonylurea
SY052679
TOLUENESULFONYLUREA
TOLBUTAMIDE IMPURITY B [EP IMPURITY]
SCHEMBL170426
N-(p-Toluenesulfonyl)urea
EINECS 216-900-3
n-carbamoyl-4-methylbenzenesulfonamide
PB29041
4-Tolylsulfonylurea
A811098
J-523530
4-Methylphenylsulfonylurea
1-((4-METHYLPHENYL)SULFONYL)UREA

MDL Number

MFCD00196522

Customs Code

2935009090

FAQ

What is N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0)?

N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) is a sulfonamide derivative with the chemical formula C8H10N2O2S. It features a benzene ring substituted with a methyl group and a sulfonamide group, along with a carbamoyl functional group. This compound is known for its stability and is commonly used as an intermediate in organic synthesis. Its properties include moderate solubility in water and organic solvents, and it appears as a white crystalline solid at room temperature.

What are the main uses of N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0)?

N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) is primarily utilized in pharmaceutical research as a building block for drug development, particularly in the synthesis of antidiabetic and anti-inflammatory agents. It also finds applications in industrial chemical processes and as a reagent in organic research. Its utility stems from its ability to participate in various chemical reactions, making it valuable in creating complex molecules for medicinal and functional purposes.

Is N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) safe?

N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) is generally considered safe when handled properly, but it requires adherence to standard chemical safety protocols. It may exhibit mild irritancy to skin and eyes, so protective measures like gloves, safety goggles, and adequate ventilation are recommended. Safety data sheets (SDS) should be consulted for detailed handling guidelines. Compliance with OSHA and EPA regulations ensures safe use in laboratories and industrial settings.

How should N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) be stored?

N-Carbamoyl-4-methylbenzenesulfonamide (CAS: 1694-06-0) should be stored in a sealed, airtight container in a cool, dry place away from light. It is stable under normal storage conditions but should be kept at temperatures below 25°C and humidity levels under 60% to prevent degradation. Avoid exposure to moisture and ensure proper ventilation to maintain its chemical integrity and safety.