4-Chloro-3-methylpyridine

Basic Information

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CAS Number

1681-36-3

Molecular Formula

C6H6ClN

Molecular Weight

127.57 g/mol

EINECS

671-799-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

165-169°C

Boiling Point

192-193 C

Density

1,17 g/cm

Flash Point

75 ºC

Refractive Index

1,533

SMILES

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CC1=C(C=CN=C1)Cl

InChI

InChI=1S/C6H6ClN/c1-5-4-8-3-2-6(5)7/h2-4H,1H3

InChIKey

DZNXMHJMXLSNIR-UHFFFAOYSA-N

LogP

2.04342

pKa

3.44±0.10(Predicted)

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

74.9

Synonyms & References

English

A3723
4-chloro-3-methyl pyridine
CS-0061361
4-Chloro-3-picoline
SB52835
AKOS005258288
DZNXMHJMXLSNIR-UHFFFAOYSA-N
J-515015
AM20050867
F10680
4-chloro-3-methyl-pyridine
1681-36-3
AS-46836
FT-0650018
DTXSID80374014
4-Chloro-3-methylpyridine (4-Chloro-3-picoline)
EN300-106148
SCHEMBL112214
3-methyl-4-chloropyridine
4-chloro-3-methylpyridine
AB11511
MFCD02183558
PYRIDINE, 4-CHLORO-3-METHYL-
4-CHLORO-3-PICOLINE
4-CHLORO-3-METHYLPYRIDINE
3-Methyl-4-ChloropyridineHydrochloride
3-methyl-4-chloropyridine HCl
4-Chloro-3-methylpyridine HCl Salt
4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE)
4-chloro-3-picoline HCI
4-Chloro-5-methylpyridine

MDL Number

MFCD02183558

EC Number

671-799-7

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 4-Chloro-3-methylpyridine (CAS: 1681-36-3)?

4-Chloro-3-methylpyridine (CAS: 1681-36-3) is classified by the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a skin and eye irritant. It is also regulated under the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) in the European Union. In the United States, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines regarding its handling and use. Compliance with these regulations is essential to ensure safety and legal compliance.

Are there alternatives to 4-Chloro-3-methylpyridine (CAS: 1681-36-3) in synthesis?

Several alternatives to 4-Chloro-3-methylpyridine can be used in synthesis, depending on the specific requirements of the reaction. Common substitutes include 4-Methylpyridine, 3-Chloropyridine, and 2-Chloro-3-methylpyridine. These alternatives offer similar functional groups but may have different reactivity and solubility properties, making them suitable for various applications.

What is the market or research trend for 4-Chloro-3-methylpyridine (CAS: 1681-36-3)?

The market for 4-Chloro-3-methylpyridine (CAS: 1681-36-3) is driven by its use in the pharmaceutical and agrochemical industries. Recent research trends focus on the development of new synthetic methods and its application in the synthesis of biologically active compounds. Price trends are influenced by global supply and demand dynamics, with increasing demand in emerging markets driving prices upward. Emerging markets in Asia and South America are expected to see significant growth in the near future.

How should waste containing 4-Chloro-3-methylpyridine (CAS: 1681-36-3) be handled?

Waste containing 4-Chloro-3-methylpyridine (CAS: 1681-36-3) should be collected in appropriate containers and properly labeled as hazardous. Incineration is a common method for disposal, but professional waste disposal services are recommended for safety and compliance. Environmental protection precautions include ensuring proper ventilation and using personal protective equipment (PPE) during handling. Strict adherence to local regulations and guidelines is essential to prevent environmental contamination and ensure worker safety.