N6-Carbobenzoxy-L-lysine N-Carboxyanhydride

Basic Information

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CAS Number

1676-86-4

Molecular Formula

C15H18N2O5

Molecular Weight

306.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.248

SMILES

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C1=CC=C(C=C1)COC(=O)NCCCCC2C(=O)OC(=O)N2

InChI

InChI=1S/C15H18N2O5/c18-13-12(17-15(20)22-13)8-4-5-9-16-14(19)21-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2,(H,16,19)(H,17,20)

InChIKey

HLLIDIRDRPSCHN-UHFFFAOYSA-N

LogP

1.7181

Topological Polar Surface Area

93.72999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

407

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N6-Carbobenzoxy-L-lysine N-Carboxyanhydride
benzyl N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]carbamate
L-N- Benzoyloxycarbonyl Lysine N-Carboxyanhydride
Lys(Z)-NCA
A-Benzyloxycarbonyl-L-lysine
A-Benzyloxycarbonyl-L-lysine Carboxyanhydride
A-Benzyloxycarbonyl-L-lysine N-Carboxyanhydride
A-Carbobenzoxylysine N-Carboxy Anhydride
NCA-N-
K(Z)-NCA
Lys(Cbz)-NCA
L-Lys(Cbz)-NCA
(S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate
(S)-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid Phen
L-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid Benzyl Ester
N-[(4S)-4-(2,5-Dioxo-4-oxazolidinyl)butyl]carbaMic Acid PhenylMethyl Ester
L-N-Benzoyloxycarbonyl lysine n-carboxyanhydride
AK313812
(S)-4-[4-(Cbz-amino)butyl]oxazolidine-2,5-dione
VZ33005
N
A-Benzyloxycarbonyl-L-lysine N-Carboxya
N6-Carbobenzoxy-L-lysine N-carboxyanhydride
1676-86-4
BENZYL N-{4-[(4S)-2,5-DIOXO-1,3-OXAZOLIDIN-4-YL]BUTYL}CARBAMATE
DTXSID20433230
MFCD16036317
HY-W092115
(S)-Benzyl(4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate
Benzyl {4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl}carbamate
AKOS027322593

MDL Number

MFCD16036317

FAQ

What regulatory guidelines apply to N6-Carbobenzoxy-L-lysine N-Carboxyanhydride (CAS: 1676-86-4)?

N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it falls under Category 2 for skin corrosion/irritation. Additionally, it is regulated under the REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) framework in the EU, requiring suppliers to provide safety data sheets (SDS) and register the chemical if the annual production or import exceeds one tonne. In the USA, the FDA and EPA may have specific requirements related to its handling and disposal based on its potential use in pharmaceuticals or other applications.

Are there alternatives to N6-Carbobenzoxy-L-lysine N-Carboxyanhydride (CAS: 1676-86-4) in synthesis?

Yes, there are alternatives to N6-Carbobenzoxy-L-lysine N-Carboxyanhydride in synthesis. Common alternatives include N-Carbobenzoxy-L-lysine and other lysine derivatives like N-Cbz-L-arginine. These alternatives can be used in peptide synthesis as protecting groups, but the choice depends on the specific reaction conditions and the desired product. Other reagents like N-Methyl-L-lysine N-carboxyanhydride may also be considered based on the application.

What is the market or research trend for N6-Carbobenzoxy-L-lysine N-Carboxyanhydride (CAS: 1676-86-4)?

The market for N6-Carbobenzoxy-L-lysine N-Carboxyanhydride is driven by its use in peptide synthesis and drug development. Research trends indicate a growing interest in developing peptide-based therapeutics, which has increased the demand for this compound. Market trends show steady growth due to its importance in the pharmaceutical industry. Emerging research is focusing on the optimization of synthetic methods and the exploration of its use in biotechnology and biopharmaceutical applications.

How should waste containing N6-Carbobenzoxy-L-lysine N-Carboxyanhydride (CAS: 1676-86-4) be handled?

Waste containing N6-Carbobenzoxy-L-lysine N-Carboxyanhydride should be handled according to local and international regulations. Collection should be done in appropriate containers, ensuring minimal spillage. For disposal, the waste should be treated by incineration or through a professional waste disposal service that specializes in chemical waste. Environmental precautions include ensuring that no residues contaminate soil or water. Always consult the safety data sheet (SDS) for specific handling instructions and local regulations.