Ethyl 5-nitro-1H-indole-2-carboxylate

Basic Information

View in Editor

CAS Number

16732-57-3

Molecular Formula

C11H10N2O4

Molecular Weight

234.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

220-225 ºC

Boiling Point

429.5℃ at 760 mmHg

Flash Point

213.5℃

Refractive Index

1.5300 (estimate)

SMILES

View in Editor

CCOC(=O)C1=CC2=C(N1)C=CC(=C2)[N+](=O)[O-]

InChI

InChI=1S/C11H10N2O4/c1-2-17-11(14)10-6-7-5-8(13(15)16)3-4-9(7)12-10/h3-6,12H,2H2,1H3

InChIKey

DVFJMQCNICEPAI-UHFFFAOYSA-N

LogP

2.77600

Complexity

315

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

BCP31397
ETHYL-5-NITRO-1H-INDOLE-2-CARBOXYLATE
5-Nitro-1H-indole-2-carboxylic acid ethyl ester
FT-0637413
ethyl 5-nitroindole-2-carboxylate
AKOS005135664
AMY9797
N-3303
STR05636
2-Ethoxycarbonyl-5-nitroindole
ethyl 5-nitro-1H-indole 2-carboxylate
5-nitroindole-2-carboxylic acid ethyl ester
NSC131897
PS-4214
Oprea1_174962
CS-W006357
ethyl5-nitro-1H-indole-2-carboxylate
Ethyl 5-Nitroindole-2-Carbonate
AC-7290
5-Nitroindole-2-carboxylic acid ethyl ester;Ethyl 5-nitro-1H-indole-2-carboxylate
ethyl 5-nitro-2-indolecarboxylate
A3709
CCG-236934
5-nitro-indole-2-carboxylic acid ethyl ester
5-nitro-2-indolecarboxylic acid ethyl ester
1H-Indole-2-carboxylic acid, 5-nitro-, ethyl ester
DTXSID80299657
DVFJMQCNICEPAI-UHFFFAOYSA-N
E1176
ethyl 5-nitro-1H-indole-2-carboxylate
ethyl-5-nitroindole-2-carboxylate

MDL Number

MFCD00216477

Customs Code

2933990090

FAQ

What regulatory guidelines apply to Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3)?

Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) is subject to various regulatory guidelines, including GHS classification, which categorizes it based on its physical and health hazards. In the European Union, it falls under the REACH regulations, requiring manufacturers and importers to register substances above a certain tonnage. Additionally, the FDA and EPA have specific requirements for the handling, storage, and disposal of this compound to ensure safety and environmental protection.

Are there alternatives to Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) in synthesis?

In synthesis, Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) can be replaced by analogous compounds such as Ethyl 5-aminomethyl-1H-indole-2-carboxylate or similar derivatives. Common alternative reagents include nitroso compounds and other aromatic carboxylic acids, which can serve as precursors in similar reactions.

What is the market or research trend for Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3)?

The market trend for Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) is closely linked with its use in medicinal chemistry and pharmaceutical research. Increasing research into indole derivatives, particularly those containing nitro groups, indicates a growing interest in this compound for drug development. Additionally, there is a trend towards exploring its potential applications in agrochemicals and materials science.

How should waste containing Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) be handled?

Waste containing Ethyl 5-nitro-1H-indole-2-carboxylate (CAS: 16732-57-3) should be collected in appropriate containers and stored separately from other materials. Incineration is a common method for disposal, but it should be performed in a controlled environment to minimize environmental impact. Professional waste disposal services are recommended to ensure compliance with environmental regulations and safety standards. Proper labeling and documentation of the waste are also essential.