Anidulafungin | CAS No. 166663-25-8

Anidulafungin

Basic Information

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CAS Number

166663-25-8

Molecular Formula

C58H73N7O17

Molecular Weight

1140.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

1477°C at 760 mmHg

Solubility

Practically insoluble

SMILES

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CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)NC4CC(C(NC(=O)C5C(C(CN5C(=O)C(NC(=O)C(NC(=O)C6CC(CN6C(=O)C(NC4=O)C(C)O)O)C(C(C7=CC=C(C=C7)O)O)O)C(C)O)C)O)O)O

InChI

InChI=1S/C58H73N7O17/c1-5-6-7-24-82-40-22-18-35(19-23-40)33-10-8-32(9-11-33)34-12-14-37(15-13-34)51(74)59-41-26-43(70)54(77)63-56(79)47-48(71)29(2)27-65(47)58(81)45(31(4)67)61-55(78)46(50(73)49(72)36-16-20-38(68)21-17-36)62-53(76)42-25-39(69)28-64(42)57(80)44(30(3)66)60-52(41)75/h8-23,29-31,39,41-50,54,66-73,77H,5-7,24-28H2,1-4H3,(H,59,74)(H,60,75)(H,61,78)(H,62,76)(H,63,79)/t29-,30+,31+,39+,41-,42-,43+,44-,45-,46-,47-,48-,49-,50-,54+/m0/s1

InChIKey

JHVAMHSQVVQIOT-MFAJLEFUSA-N

LogP

-0.9270999999999889

Topological Polar Surface Area

377.4200000000001 Å²

Hydrogen Bond Donor/Acceptor

14 / 24

Complexity

2150

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

ANIDULAFUNGIN [USAN]
UNII-9HLM53094I
Anidulafungina
DTXSID50873201
J02AX06
NCGC00386349-01
Anidulafungin (LY303366)
N-[[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-tetrahydroxy-bis[(1R)-1-hydroxyethyl]-methyl-hexaoxo-[?]yl]-4-[4-(4-pentoxyphenyl)phenyl]benzamide
BDBM50417554
LY-303366
Anidulafungin
ANIDULAFUNGIN [MART.]
N-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-3,15-bis[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0,9,13]heptacosan-18-yl]-4'-[4-(pentyloxy)phenyl]-[1,1'-biphenyl]-4-carboxamide
Anidulafunginum
ANIDULAFUNGIN [WHO-DD]
DB00362
ANIDULAFUNGIN [VANDF]
VER-002
ANIDULAFUNGIN (MART.)
Anidulafungin [USAN:INN:BAN]
SW222238-1
LY303366
166663-25-8
Ecalta
D-70013
CS-1824
Q4764531
VER002
Anidulafungine
Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-
ECHINOCANDIN B, 1-((4R,5R)-4,5-DIHYDROXY-N(SUP 2)-((4''-(PENTYLOXY)(1,1':4',1''-TERPHENYL)-4-YL)CARBONYL)-L-ORNITHINE)-

MDL Number

MFCD00917070

FAQ

What is Anidulafungin (CAS: 166663-25-8)?

Anidulafungin is an antifungal medication used to treat various types of fungal infections. It belongs to the class of echinocandins and has the chemical formula C29H34N2O7. Anidulafungin works by inhibiting the synthesis of fungal cell walls, which are primarily composed of β-(1,3)-D-glucan. It is known for its broad-spectrum activity against Candida species and Aspergillus fumigatus.

What are the main uses of Anidulafungin (CAS: 166663-25-8)?

Anidulafungin is primarily used for treating invasive candidiasis, including candidemia, and as an adjunct therapy for esophageal candidiasis. It is also indicated for the treatment of Aspergillus fumigatus infections, especially in patients with severe underlying health conditions. This medication is administered intravenously or orally depending on the patient's condition.

Is Anidulafungin (CAS: 166663-25-8) safe?

Anidulafungin is generally well-tolerated, but like all medications, it can cause side effects. Common side effects include injection site reactions, headache, and nausea. Serious side effects can include allergic reactions and liver function abnormalities. It is important to follow medical advice and adhere to prescribed dosages to ensure safe use. Always consult a healthcare provider for specific safety guidelines related to your condition and medication use.

How should Anidulafungin (CAS: 166663-25-8) be stored?

Anidulafungin should be stored at room temperature, between 15°C and 30°C (59°F and 86°F). It should be kept away from direct sunlight and moisture to maintain its stability. The medication should be stored in a tightly closed container and protected from light. Follow the manufacturer's instructions for storage to ensure the efficacy and safety of the medication.