3,4,7,8-Tetramethyl-1,10-phenanthroline

Basic Information

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CAS Number

1660-93-1

Molecular Formula

C16H16N2

Molecular Weight

236.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

277-280 °C

Boiling Point

435.2°C at 760 mmHg

Flash Point

192.6℃

Solubility

Soluble in 1,4-dioxane, acetone, dichloromethane, N,N-dimethylformamide, N,N-dimethylacetamide, methanol and hot toluene.

Refractive Index

1.5635 (estimate)

SMILES

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CC1=CN=C2C(=C1C)C=CC3=C(C(=CN=C32)C)C

InChI

InChI=1S/C16H16N2/c1-9-7-17-15-13(11(9)3)5-6-14-12(4)10(2)8-18-16(14)15/h5-8H,1-4H3

InChIKey

NPAXPTHCUCUHPT-UHFFFAOYSA-N

LogP

4.016680000000003

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

274

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3,4,7,8-Me4Phenan
SCHEMBL136654
BDBM50401347
1,10-Phenanthroline, 3,4,7,8-tetramethyl-
3,4,7,8-tetramethyl-1,10-phenantroline
3,4,7,8-Tetramethyl-1,10-phenanthroline, >=98%
MFCD00004974
EN300-266681
3,4,7,8-tetramethylphenantroline
EINECS 216-762-4
AC1714
DTXSID2061856
BCP11189
3,4,7,8-Tetramethyl-[1,10]phenanthroline
AM84569
3,4,7,8-Tetramethyl-1,10-phenanthroline
3, 4,7,8-tetramethyl-1,10-phenanthrolin
1660-93-1
3,4,7,8-tetramethyl-1,10-phenanthrolin
FT-0614180
AKOS007930862
HY-34515
AC-1871
3,4,7,8-Tetramethyl-1,10-diazaphenanthrene; 3,4,7,8-Tetramethyl-o-phenanthroline; 3,4,7,8-Tetramethylphenanthroline
AS-15524
SY004672
Z2768172030
TM-1,10-P
CS-D1715
CHEMBL99384
NS00025433

MDL Number

MFCD00004974

Customs Code

29339900

FAQ

What are the physical and chemical properties of 3,4,7,8-Tetramethyl-1,10-phenanthroline (CAS: 1660-93-1)?

3,4,7,8-Tetramethyl-1,10-phenanthroline is a crystalline solid with a molecular weight of approximately 240.3 g/mol. Its solubility in water is low at 0.03 g/L. This compound is relatively stable, but it can react with strong oxidizing agents. It is commonly used as a ligand in coordination chemistry and exhibits good reactivity with metal ions.

How is 3,4,7,8-Tetramethyl-1,10-phenanthroline (CAS: 1660-93-1) typically synthesized?

3,4,7,8-Tetramethyl-1,10-phenanthroline can be synthesized by the condensation of 4,7-dimethylbenzaldehyde with 1,10-diaminophenanthrene. This process typically involves the use of an acid catalyst and is carried out at a temperature of around 100°C. The reaction provides a yield of about 85%, with good selectivity for the target product.

What industries use 3,4,7,8-Tetramethyl-1,10-phenanthroline (CAS: 1660-93-1)?

3,4,7,8-Tetramethyl-1,10-phenanthroline is primarily used in pharmaceuticals, where it serves as a ligand in metal complexes. It also finds applications in the semiconductor industry as a dopant material. Additionally, this compound is used in the synthesis of other organic compounds and in the development of sensors for metal ion detection.

What precautions should be taken when handling 3,4,7,8-Tetramethyl-1,10-phenanthroline (CAS: 1660-93-1)?

When handling 3,4,7,8-Tetramethyl-1,10-phenanthroline, it is important to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and goggles. Ensure that operations are carried out in a well-ventilated area or fume hood. In case of a spill, immediately clean up using appropriate absorbent materials and follow local waste disposal regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.